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[猪实验性气溶胶感染胸膜肺炎放线杆菌后临床、影像学和超声检查结果的诊断意义比较]

[Comparison of the diagnostic significance of clinical, radiographic and ultrasonographic results after an experimental aerosol infection of pigs with Actinobacillus pleuropneumoniae].

作者信息

Höltig D, Hennig-Pauka I, Beyerbach M, Thies K, Rehm T, Gerlach G-F, Waldmann K-H

机构信息

Klinik für Kleine Klauentiere und Forensische Medizin und Ambulatorische Klinik, Stiftung Tierärztliche Hochschule Hannover.

出版信息

Berl Munch Tierarztl Wochenschr. 2008 Nov-Dec;121(11-12):422-31.

Abstract

Scoring schemes for clinical, ultrasonographic and radiographic findings in pigs were developed based upon a standardized animal model for Actinobacillus pleuropneumoniae infection.The results of these methods were compared to each other as well as with the corresponding pathomorphological findings during necropsy. Altogether 69 pigs of different breeding lines (Hampshire, Pietrain and German Landrace were examined. Positive correlations were found between the results of all three methods as well as with the necropsy scores (p <0.0001). Different pathomorphological findings were detected either by radiographic or by ultrasonographic examination dependent upon the type of lung tissue alterations: Alterations of the pleura as well as sequestration of lung tissue on the lung surface could be clearly identified during the ultrasonographic examination while deep tissue alterations with no contact to the lung surface could be detected reliably by radiographic examination. Both methods complement each other, and the application of a combined ultrasonographic and radiographic examination of the thorax allows a comprehensive inspection of the lung condition. Particularly during the acute phase of the disease the extent of lung tissue damage can be estimated more precisely than by clinical examination alone.

摘要

基于胸膜肺炎放线杆菌感染的标准化动物模型,制定了猪临床、超声和放射学检查结果的评分方案。将这些方法的结果相互比较,并与尸检时相应的病理形态学结果进行比较。共检查了69头不同品系(汉普夏、皮特兰和德国长白猪)的猪。发现所有三种方法的结果与尸检评分之间均存在正相关(p<0.0001)。根据肺组织改变的类型,通过放射学或超声检查可检测到不同的病理形态学结果:超声检查可清晰识别胸膜改变以及肺表面肺组织的隔离,而放射学检查可可靠检测到与肺表面无接触的深部组织改变。两种方法相互补充,胸部超声和放射学联合检查的应用可全面检查肺部状况。特别是在疾病的急性期,与仅通过临床检查相比,可更精确地估计肺组织损伤的程度。

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