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¹⁸F-氟脱氧葡萄糖正电子发射断层扫描-计算机断层扫描在患有肺炎的小型猪(家猪)中的应用。

Use of ¹⁸F-fluorodeoxyglucose positron emission tomography-computed tomography in a miniature pig (Sus scrofa domestica) with pneumonia.

作者信息

Kim Jong-In, Lee Young Ah, Lee Jae Won, Jeong Sang Min, Chung Hyun Woo, Han Jin Soo

机构信息

Department of Laboratory Animal Medicine & Institute for the 3Rs, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea.

出版信息

Comp Med. 2012 Jun;62(3):203-8.

Abstract

A 1-y-old male miniature pig housed in our laboratory facility was evaluated for weight loss and rough coat condition. CBC results revealed neutrophilia. Radiography of the thoracic area showed increased opacity throughout the thoracic cavity except for the right caudal lobe. ¹⁸F-labeled fluorodeoxyglucose positron emission tomography-computed tomography (FDG-PET-CT) revealed elevated standard uptake values in the area corresponding to the radiologic findings. Follow-up thoracic radiography taken 2 wk after FDG-PET-CT showed several interval changes, including markedly decreased opacity throughout the entire thoracic cavity. Necropsy revealed adhesions between the upper portion of the caudal lobe of the left lung and thoracic wall. ELISA for several closely related infectious species confirmed the presence of antibody to Actinobacillus pleuropneumoniae serovar V.

摘要

对饲养在我们实验室设施中的一头1岁雄性小型猪进行了体重减轻和被毛粗糙状况的评估。全血细胞计数结果显示嗜中性粒细胞增多。胸部X线检查显示,除右尾叶外,整个胸腔的不透明度增加。¹⁸F标记的氟脱氧葡萄糖正电子发射断层扫描-计算机断层扫描(FDG-PET-CT)显示,在与放射学检查结果相对应的区域,标准摄取值升高。在FDG-PET-CT检查后2周进行的后续胸部X线检查显示有几个间隔变化,包括整个胸腔的不透明度明显降低。尸检发现左肺尾叶上部与胸壁之间有粘连。对几种密切相关的感染性物种进行的酶联免疫吸附测定证实存在胸膜肺炎放线杆菌血清型V抗体。

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