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3
Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: spontaneous recovery after spinal cord injury and statistical power needed for therapeutic clinical trials.国际脊髓损伤协作组制定的脊髓损伤临床试验实施指南:脊髓损伤后的自然恢复及治疗性临床试验所需的统计效力
Spinal Cord. 2007 Mar;45(3):190-205. doi: 10.1038/sj.sc.3102007. Epub 2006 Dec 19.
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Targeting recovery: priorities of the spinal cord-injured population.以恢复为目标:脊髓损伤人群的优先事项。
J Neurotrauma. 2004 Oct;21(10):1371-83. doi: 10.1089/neu.2004.21.1371.
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Long-term exercise training in persons with spinal cord injury: effects on strength, arm ergometry performance and psychological well-being.脊髓损伤患者的长期运动训练:对力量、手臂测力计性能和心理健康的影响。
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7
Fatty acid kinetics and carbohydrate metabolism during electrical exercise in spinal cord-injured humans.脊髓损伤患者进行电刺激运动时的脂肪酸动力学和碳水化合物代谢
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Validity of inspiratory and expiratory methods of measuring gas exchange with a computerized system.使用计算机系统测量气体交换的吸气和呼气方法的有效性。
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9
Cardiovascular responses at the onset of passive leg cycle exercise in paraplegics with spinal cord injury.
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10
Cardiovascular and respiratory responses to passive leg cycle exercise in people with spinal cord injuries.
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一种新型康复设备对脊髓损伤患者的疗效。

Efficacy of a new rehabilitative device for individuals with spinal cord injury.

作者信息

Astorino Todd A, Tyerman Nick, Wong Keau, Harness Eric

机构信息

California State University San Marcos, Department of Kinesiology, San Marcos, CA 92096-0001, USA.

出版信息

J Spinal Cord Med. 2008;31(5):586-91.

PMID:19086717
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2607132/
Abstract

BACKGROUND/OBJECTIVE: Regular exercise is required in persons with spinal cord injury (SCI) to reduce the deleterious effects of chronic paralysis. The primary aims of the study were to examine responses to passive and active exercise on a new rehabilitative device for persons with SCI and to examine reliability of these responses over 2 days of testing.

METHODS

Nine men and women with chronic SCI completed the study, 2 with a complete injury and 7 with an incomplete injury. The level of injury ranged from thoracic (T4-T6 and T10) to cervical (4 with C5-C6 and 3 with C6-C7 injuries). They completed 2 30-minute sessions of active lower-body and passive upper-body exercise, during which heart rate (HR), blood pressure (BP), gas exchange data, rating of perceived exertion (RPE), and oxygen-hemoglobin saturation were continuously assessed.

DATA ANALYSIS

One-way ANOVA with repeated measures was used to examine differences in all variables over time.

RESULTS

Results demonstrated significant increases (P < 0.05) in HR, systolic BP, RPE, and oxygen uptake (V(O2)) from rest to exercise. No change (P > 0.05) in diastolic BP or oxygen-hemoglobin saturation was evident. Cronbach's alpha values for HR, systolic BP, and V(O2) recorded over both days of testing ranged from 0.79 to 0.97, indicating adequate consistency.

CONCLUSIONS

Data demonstrated that exercise on this device significantly increases HR, V(O2), and systolic BP compared to rest. However, its efficacy for long-term rehabilitation, especially in regular exercisers with SCI, is unknown.

摘要

背景/目的:脊髓损伤(SCI)患者需要定期锻炼以减轻慢性瘫痪的有害影响。本研究的主要目的是检验SCI患者在一种新型康复设备上对被动和主动运动的反应,并检验这些反应在两天测试中的可靠性。

方法

9名慢性SCI患者完成了本研究,其中2例为完全性损伤,7例为不完全性损伤。损伤平面从胸段(T4 - T6和T10)到颈段(4例C5 - C6损伤,3例C6 - C7损伤)。他们完成了2次30分钟的主动下半身和被动上半身锻炼,在此期间持续评估心率(HR)、血压(BP)、气体交换数据、主观用力程度分级(RPE)和氧合血红蛋白饱和度。

数据分析

采用重复测量的单因素方差分析来检验所有变量随时间的差异。

结果

结果表明,从静息状态到运动状态,HR、收缩压、RPE和摄氧量(V(O2))显著增加(P < 0.05)。舒张压或氧合血红蛋白饱和度无明显变化(P > 0.05)。在两天测试中记录的HR、收缩压和V(O2)的Cronbach's α值范围为0.79至0.97,表明具有足够的一致性。

结论

数据表明,与静息状态相比,在该设备上进行锻炼可显著提高HR、V(O2)和收缩压。然而,其对长期康复的疗效,尤其是对有规律锻炼的SCI患者,尚不清楚。