Kumar Aryavarta M S, Fox Justin D, Buerkle Lauren E, Marchant Roger E, Rowan Stuart J
Department of Biomedical Engineering, Department of Macromolecular Science and Engineering, Case Western Reserve University, Cleveland, Ohio 44106, USA.
Langmuir. 2009 Jan 20;25(2):653-6. doi: 10.1021/la803369j.
The self-assembly of high aspect ratio hierarchical surface assemblies, as observed by fluid tapping mode AFM, can be achieved through careful design of the supramolecular interactions between low-molecular-weight adsorbates. Needlelike assemblies of monotopic guanine end-capped alkanes grow on a graphite surface when deposited from a water/DMSO solution. The growth of these assemblies can be monitored by AFM in real time, and the growth rate along the two different axes can be understood (through molecular modeling) in terms of the specific adsorbate-adsorbate interactions along those axes. Additionally, through judicious solvent selection (e.g., use of non-H-bonding solvents such as o-dichlorobenzene), which allows the formation of hydrogen-bonding aggregates in solution and influences the surface-adsorbate interactions, dramatically different surface assemblies of these guanine derivatives are obtained.
通过流体敲击模式原子力显微镜观察到，高纵横比分级表面组装体的自组装可以通过精心设计低分子量吸附物之间的超分子相互作用来实现。当从水/二甲基亚砜溶液中沉积时，单官能团鸟嘌呤封端的烷烃的针状组装体在石墨表面生长。这些组装体的生长可以通过原子力显微镜实时监测，并且（通过分子建模）可以根据沿这些轴的特定吸附物 - 吸附物相互作用来理解沿两个不同轴的生长速率。此外，通过明智地选择溶剂（例如使用邻二氯苯等非氢键溶剂），这允许在溶液中形成氢键聚集体并影响表面 - 吸附物相互作用，从而获得这些鸟嘌呤衍生物的截然不同的表面组装体。
