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低剂量局部麻醉药普通溶液用于俯卧位脊髓麻醉:布比卡因与左旋布比卡因的比较

The use of low dose plain solutions of local anaesthetic agents for spinal anaesthesia in the prone position: bupivacaine compared with levobupivacaine.

作者信息

Cuvas O, Gulec H, Karaaslan M, Basar H

机构信息

Department of Anaesthesiology and Intensive Care Medicine, Ankara Training and Research Hospital, Ankara, Turkey.

出版信息

Anaesthesia. 2009 Jan;64(1):14-8. doi: 10.1111/j.1365-2044.2008.05680.x.

DOI:10.1111/j.1365-2044.2008.05680.x
PMID:19087000
Abstract

In this study, we aimed to test the hypothesis that 1-ml plain solution of 0.5% bupivacaine or 0.5% levopubivacaine administered in a subarachnoid block can provide adequate anaesthesia and operating conditions for pilonidal cyst/sinus operations performed in the prone position. There were no significant differences between the two groups in terms of patient demographic data, duration of operation, patient-surgeon satisfaction, haemodynamic changes and side effects. There were no significant differences found in the onset time, highest block level achieved, two segment regression, time to S(2) regression of sensory block and the number of anaesthetised dermatomes, between the two groups (p = 0.077, 0.057, 0.091, 0.084 and 0.057 respectively). The incidence of complete motor blockade was 16% and 8% in Group B at the start and at the end of the operation. There was no complete motor blockade in Group L (p = 0.110 and 0.490 respectively). We conclude that both regimens are effective and safe for use in subarachnoid anaesthesia for pilonidal cyst/sinus operations performed in the prone position.

摘要

在本研究中,我们旨在验证以下假设:蛛网膜下腔阻滞时给予1毫升0.5%布比卡因或0.5%左旋布比卡因的单纯溶液可为俯卧位行藏毛窦/藏毛囊肿手术提供充分的麻醉和手术条件。两组患者的人口统计学数据、手术时长、患者-外科医生满意度、血流动力学变化及副作用方面均无显著差异。两组在起效时间、达到的最高阻滞平面、两个节段的消退情况、感觉阻滞至S(2)消退的时间以及麻醉皮节数量方面均未发现显著差异(p值分别为0.077、0.057、0.091、0.084和0.057)。B组手术开始时和结束时完全运动阻滞的发生率分别为16%和8%。L组未出现完全运动阻滞(p值分别为0.110和0.490)。我们得出结论,两种方案用于俯卧位行藏毛窦/藏毛囊肿手术的蛛网膜下腔麻醉均有效且安全。

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