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2004-2005 年全爱尔兰肌萎缩侧索硬化症流行病学研究。

An all-Ireland epidemiological study of MND, 2004-2005.

机构信息

Department of Neurology, Royal Victoria Hospital, Belfast, UK.

出版信息

Eur J Neurol. 2009 Jan;16(1):148-53. doi: 10.1111/j.1468-1331.2008.02361.x.

Abstract

BACKGROUND AND METHODS

We conducted an all-Ireland population-based prospective epidemiological survey of motor neurone disease (MND) using the Northern Ireland and Republic of Ireland MND registers to examine the incidence and prevalence of the disease over the period 2004-2005.

RESULTS AND CONCLUSIONS

Incidence of MND was 1.9 per 100 000 person-years and rates were comparable in both the north and south of Ireland. Prevalence of MND was 5.0 per 100 000 population. When compared with previous published surveys of MND performed in the Republic of Ireland over the last 10 years, rates of disease have remained relatively constant. When standardized to the 1990 US population, the incidence of MND in Ireland was found to be consistent with other European prospective surveys of MND.

摘要

背景与方法

我们利用北爱尔兰和爱尔兰共和国的运动神经元疾病(MND)登记处,进行了一项全爱尔兰基于人群的前瞻性流行病学调查,以研究 2004-2005 年期间该病的发病率和患病率。

结果与结论

MND 的发病率为每 100000 人年 1.9 例,南北爱尔兰的发病率相当。MND 的患病率为每 100000 人 5.0 例。与过去 10 年在爱尔兰共和国进行的 MND 先前发表的调查相比,疾病的发病率相对保持稳定。与 1990 年美国人口相比,爱尔兰的 MND 发病率与其他欧洲前瞻性 MND 调查一致。

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