• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Low density lipoprotein receptor polymorphisms and the risk of coronary heart disease: the Atherosclerosis Risk in Communities Study.

作者信息

Franceschini N, Muallem H, Rose K M, Boerwinkle E, Maeda N

出版信息

J Thromb Haemost. 2009 Mar;7(3):496-8. doi: 10.1111/j.1538-7836.2008.03262.x.

DOI:10.1111/j.1538-7836.2008.03262.x
PMID:19087220
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2656439/
Abstract
摘要

相似文献

1
Low density lipoprotein receptor polymorphisms and the risk of coronary heart disease: the Atherosclerosis Risk in Communities Study.低密度脂蛋白受体基因多态性与冠心病风险：社区动脉粥样硬化风险研究
J Thromb Haemost. 2009 Mar;7(3):496-8. doi: 10.1111/j.1538-7836.2008.03262.x.
2
Interaction of folate intake and the paraoxonase Q192R polymorphism with risk of incident coronary heart disease and ischemic stroke: the atherosclerosis risk in communities study.叶酸摄入量与对氧磷酶 Q192R 多态性与冠心病和缺血性卒中发病风险的交互作用：社区动脉粥样硬化风险研究。
Ann Epidemiol. 2011 Nov;21(11):815-23. doi: 10.1016/j.annepidem.2011.08.007.
3
Sequence variation in telomerase reverse transcriptase (TERT) as a determinant of risk of cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study.端粒酶逆转录酶（TERT）基因序列变异作为心血管疾病风险的决定因素：社区动脉粥样硬化风险（ARIC）研究
BMC Med Genet. 2015 Jul 23;16:52. doi: 10.1186/s12881-015-0194-x.
4
CYP2J2 and CYP2C8 polymorphisms and coronary heart disease risk: the Atherosclerosis Risk in Communities (ARIC) study.CYP2J2和CYP2C8基因多态性与冠心病风险：社区动脉粥样硬化风险（ARIC）研究
Pharmacogenet Genomics. 2007 May;17(5):349-58. doi: 10.1097/FPC.0b013e32809913ea.
5
Increased risk of incident stroke associated with the cyclooxygenase 2 (COX-2) G-765C polymorphism in African-Americans: the Atherosclerosis Risk in Communities Study.非裔美国人中与环氧化酶2（COX-2）G-765C基因多态性相关的中风发病风险增加：社区动脉粥样硬化风险研究
Atherosclerosis. 2008 Feb;196(2):926-30. doi: 10.1016/j.atherosclerosis.2007.02.010. Epub 2007 Mar 9.
6
Cyclooxygenase polymorphisms and risk of cardiovascular events: the Atherosclerosis Risk in Communities (ARIC) study.环氧化酶基因多态性与心血管事件风险：社区动脉粥样硬化风险（ARIC）研究
Clin Pharmacol Ther. 2008 Jan;83(1):52-60. doi: 10.1038/sj.clpt.6100221. Epub 2007 May 9.
7
Lack of associations of ten candidate coronary heart disease risk genetic variants and subclinical atherosclerosis in four US populations: the Population Architecture using Genomics and Epidemiology (PAGE) study.四项美国人群研究（人口基因组学和流行病学研究 [PAGE]）中，十种候选冠心病风险遗传变异与亚临床动脉粥样硬化之间缺乏关联。
Atherosclerosis. 2013 Jun;228(2):390-9. doi: 10.1016/j.atherosclerosis.2013.02.038. Epub 2013 Mar 13.
8
Local Ancestry and Clinical Cardiovascular Events Among African Americans From the Atherosclerosis Risk in Communities Study.社区动脉粥样硬化风险研究中非洲裔美国人的局部血统与临床心血管事件
J Am Heart Assoc. 2017 Apr 10;6(4):e004739. doi: 10.1161/JAHA.116.004739.
9
Coronary heart disease and genetic variants with low phospholipase A2 activity.冠心病与低磷脂酶A2活性的基因变异体
N Engl J Med. 2015 Jan 15;372(3):295-6. doi: 10.1056/NEJMc1409673.
10
Genetic and environmental determinants of lipid profile in black and white youth: a study of four candidate genes.黑人和白人青年血脂谱的遗传和环境决定因素：四个候选基因的研究
Ethn Dis. 2005 Autumn;15(4):568-77.

引用本文的文献

1
Shared genetic loci connect cardiovascular disease with blood pressure and lipid traits in East Asian populations.共享的基因位点将东亚人群中的心血管疾病与血压及血脂特征联系起来。
Front Genet. 2025 Jun 24;16:1635378. doi: 10.3389/fgene.2025.1635378. eCollection 2025.
2
DNA Methylation Alterations in Fractionally Irradiated Rats and Breast Cancer Patients Receiving Radiotherapy.分次照射大鼠和接受放射治疗的乳腺癌患者的 DNA 甲基化改变。
Int J Mol Sci. 2022 Dec 19;23(24):16214. doi: 10.3390/ijms232416214.
3
Perspective: DNA Copy Number Variations in Cardiovascular Diseases.观点：心血管疾病中的DNA拷贝数变异
Epigenet Insights. 2018 Dec 12;11:2516865718818839. doi: 10.1177/2516865718818839. eCollection 2018.
4
Lipid and lipoprotein abnormalities in acute lymphoblastic leukemia survivors.急性淋巴细胞白血病幸存者的脂质和脂蛋白异常
J Lipid Res. 2017 May;58(5):982-993. doi: 10.1194/jlr.M072207. Epub 2017 Mar 8.

本文引用的文献

1
Lifelong reduction of LDL-cholesterol related to a common variant in the LDL-receptor gene decreases the risk of coronary artery disease--a Mendelian Randomisation study.与低密度脂蛋白受体基因常见变异相关的低密度脂蛋白胆固醇终生降低可降低冠状动脉疾病风险——一项孟德尔随机化研究
PLoS One. 2008 Aug 20;3(8):e2986. doi: 10.1371/journal.pone.0002986.
2
Polymorphisms associated with cholesterol and risk of cardiovascular events.与胆固醇及心血管事件风险相关的多态性
N Engl J Med. 2008 Mar 20;358(12):1240-9. doi: 10.1056/NEJMoa0706728.
3
Genetic variation at the LDL receptor and HMG-CoA reductase gene loci, lipid levels, statin response, and cardiovascular disease incidence in PROSPER.普伐他汀对高胆固醇老年人血管事件及再发卒中的预防研究（PROSPER）中低密度脂蛋白受体和HMG-CoA还原酶基因位点的遗传变异、血脂水平、他汀类药物反应及心血管疾病发病率
Atherosclerosis. 2008 Sep;200(1):109-14. doi: 10.1016/j.atherosclerosis.2007.12.004. Epub 2008 Feb 7.
4
Newly identified loci that influence lipid concentrations and risk of coronary artery disease.新发现的影响血脂浓度和冠状动脉疾病风险的基因座。
Nat Genet. 2008 Feb;40(2):161-9. doi: 10.1038/ng.76. Epub 2008 Jan 13.
5
Mechanisms of disease: genetic causes of familial hypercholesterolemia.疾病机制：家族性高胆固醇血症的遗传病因
Nat Clin Pract Cardiovasc Med. 2007 Apr;4(4):214-25. doi: 10.1038/ncpcardio0836.
6
Quantitative effects of common genetic variations in the 3'UTR of the human LDL-receptor gene and their associations with plasma lipid levels in the Atherosclerosis Risk in Communities study.人类低密度脂蛋白受体基因3'非翻译区常见基因变异的定量效应及其与社区动脉粥样硬化风险研究中血浆脂质水平的关联。
Hum Genet. 2007 May;121(3-4):421-31. doi: 10.1007/s00439-007-0327-1. Epub 2007 Feb 2.
7
Familial dyslipidaemias: an overview of genetics, pathophysiology and management.家族性血脂异常：遗传学、病理生理学及管理概述
Drugs. 2006;66(15):1949-69. doi: 10.2165/00003495-200666150-00005.
8
Protease variants, LDL, and coronary heart disease.蛋白酶变体、低密度脂蛋白与冠心病。
N Engl J Med. 2006 Mar 23;354(12):1310-2. doi: 10.1056/NEJMe068026.
9
Sequence variations in PCSK9, low LDL, and protection against coronary heart disease.前蛋白转化酶枯草溶菌素9（PCSK9）的序列变异、低密度脂蛋白水平降低与冠心病预防
N Engl J Med. 2006 Mar 23;354(12):1264-72. doi: 10.1056/NEJMoa054013.
10
Monogenic hypercholesterolemia: new insights in pathogenesis and treatment.单基因高胆固醇血症：发病机制与治疗的新见解
J Clin Invest. 2003 Jun;111(12):1795-803. doi: 10.1172/JCI18925.