Xiao Hong-xi, Hu Min, Wen Wei-sheng, Niu Yu
Department of Stomatology, General Hospital of PLA, Beijing 100853, China.
Zhonghua Kou Qiang Yi Xue Za Zhi. 2008 Oct;43(10):597-600.
To observe the dynamic changes of bone density and bone strength after alveolar ridge augmentation with Titanium Nickel shake memory alloy (TiNi-SMA) distractor and acellular dermal matrix (ADM).
Twelve adult healthy male dogs were selected. After the animal model of alveolar atrophy was set up, on one side of mandible, two S-shaped distractors were placed. The diameter of S-shaped distractor was 1 mm and the rebound temperature was 33 degrees C. The ADM was placed on the distraction gap and fixed by the feet of distractors. The other side was placed only with distractors, serving as control side. Six dogs' mandibles were harvested after 1 and 3 months respectively. Dual energy X-ray absorptiometry (DEXA) was used to scan bone density around the distraction gap. Mechanical machine was used to test compression strength and elastic modulus.
Months after distraction, the bone density of upper distraction gap, distraction gap and low distraction gap were respectively (0.714 +/- 0.238) g/cm2, (0.512 +/- 0.435) g/cm2 and (0.615 +/- 0.043) g/cm2 on experimental side. The compression strength and elastic modulus were (36.54 +/- 7.32) MPa and (1674.10 +/- 256.43) MPa. All of above were higher than those of control side.
ADM can improve the bone quality, increase bone density and intensity and is an ideal guided bone regeneration(GBR) membrane for alveolar ridge augmentation with TiNi-SMA distractor.
观察镍钛形状记忆合金（TiNi-SMA）牵张器联合脱细胞真皮基质（ADM）进行牙槽嵴增高术后骨密度和骨强度的动态变化。
选取12只成年健康雄性犬。建立牙槽骨萎缩动物模型后，在下颌骨一侧放置两个S形牵张器。S形牵张器直径为1mm，回复温度为33℃。将ADM置于牵张间隙，并通过牵张器的足部固定。另一侧仅放置牵张器作为对照侧。分别在1个月和3个月后取6只犬的下颌骨。采用双能X线吸收法（DEXA）扫描牵张间隙周围的骨密度。使用力学试验机测试抗压强度和弹性模量。
牵张术后各月，实验组牵张间隙上、中、下部位的骨密度分别为（0.714±0.238）g/cm²、（0.512±0.435）g/cm²和（0.615±0.043）g/cm²。抗压强度和弹性模量分别为（36.54±7.32）MPa和（1674.10±256.43）MPa。以上各项均高于对照侧。
ADM可改善骨质量，增加骨密度和强度，是TiNi-SMA牵张器进行牙槽嵴增高术理想的引导骨再生（GBR）膜。
