Zhang Tian-ming, An Yu-zhi, Liu Hao-cheng, Wu Jiang-ping
Department of Neurosurgery, Beijing Tongren Hospital, Capital University of Medical Sciences, Beijing 100730, China.
Zhonghua Yi Xue Za Zhi. 2008 Aug 26;88(33):2309-11.
To summarize the experience in cranial-orbital approach in the treatment of optic nerve glioma.
The clinical data of 35 patients with optic nerve glioma diagnosed by CT and MRI, 26 males and 9 females; aged 13 (1 - 54), with the main clinical presentations of visual defection and ex-ophthalmo and with the courses from 1 to 36 months, who underwent operation via the cranial-orbital approach 36 times, were analyzed. The diagnosis was confirmed by pathology after operation in 35 cases. Follow-up was conducted for 3 months to 8 years.
Total resection was achieved in 29 cases, and subtotal resection in 6 cases. The surgical complications included temporary cerebrospinal fluid rhinorrhea (2 cases) and cataract (1 cases), and no ocular movement dysfunction was found. The follow-up rate was 77.1% (27/35). Three cases suffered from recurrence, spinal metastasis was found in 1 case, and 1 case died.
resection of optic nerve glioma via cranial-orbital approach is effective. However, since residual tumor may remain in the optic nerve canal, post-operative radiation therapy is recommended.
总结经颅眶入路治疗视神经胶质瘤的经验。
分析35例经CT和MRI诊断为视神经胶质瘤患者的临床资料，其中男性26例，女性9例；年龄13岁（1 - 54岁），主要临床表现为视力减退和眼球突出，病程1至36个月，行经颅眶入路手术36次。35例术后均经病理证实诊断。随访3个月至8年。
全切除29例，次全切除6例。手术并发症包括暂时性脑脊液鼻漏（2例）和白内障（1例），未发现眼球运动功能障碍。随访率为77.1%（27/35）。3例复发，1例发生脊髓转移，1例死亡。
经颅眶入路切除视神经胶质瘤有效。然而，由于视神经管内可能残留肿瘤，建议术后进行放疗。
