Holst Peter Johannes, Christensen Jan Pravsgaard, Thomsen Allan Randrup
Institut for International Sundhed, Immunologi og Mikrobiologi, Panum Instituttet, Københavns Universitet, bygning 22.5, DK-2200 København N.
Ugeskr Laeger. 2008 Nov 24;170(48):3953-6.
We may expect that the next influenza pandemic will affect about half the world's population within a year and that it will cause unpredictable mortality rates. In this perspective, we review the molecular mechanisms underlying the development of new pandemic influenza strains and a discussion on existing and future vaccination strategies directed towards prevention of pandemic influenza is presented. There is an urgent need to develop paninfluenza-specific vaccines and invest substantially in new technologies in order to better meet this threat.
我们可以预期，下一次流感大流行将在一年内影响全球约一半人口，并将导致不可预测的死亡率。从这个角度来看，我们回顾了新型大流行性流感毒株产生的分子机制，并对现有的和未来针对预防大流行性流感的疫苗接种策略进行了讨论。迫切需要开发针对所有流感病毒的疫苗，并大力投资于新技术，以便更好地应对这一威胁。
