[生物医学文献中结果的临床评估建议]

[Recommendations for the clinical evaluation of results in the biomedical literature].

作者信息

Escrig-Sos Javier, Martínez-Ramos David, Villegas-Cánovas Carmen, Miralles-Tena Juan Manuel, Rivadulla-Serrano Isabel, Daroca-José José María

机构信息

Servicio de Cirugía, Hospital General de Castellón, Castellón de la Plana, Avda. Benicàssim s/n, Castellón, Spain.

出版信息

Cir Esp. 2008 Dec;84(6):307-12. doi: 10.1016/s0009-739x(08)75040-1.

DOI:10.1016/s0009-739x(08)75040-1

PMID:19087775

Abstract

The assessment and interpretation of the results of a clinical study are a real challenge for the clinicians. In this paper we establish a general basis for a critical and reserved assessment of these, from the fundamental aspects of the design and statistics, as well as the application of the results to our own patients according to risk and benefit criteria. Main errors and the traps that should be avoided are emphasised.

摘要

对临床研究结果的评估和解读对临床医生来说是一项真正的挑战。在本文中，我们从设计和统计学的基本方面，以及根据风险和获益标准将研究结果应用于我们自己的患者等方面，为对这些结果进行批判性和谨慎性评估建立一个总体基础。文中强调了主要的错误以及应避免的陷阱。