Guo Xiao Lei, Zhong Yan Feng, Sun Yu Heng, Liu Hong Hong, Jin Bo, Liang Wei, Li Xiao Song
Department of Neurology, Beijing Jishuitan Hospital, Peking University Fourth Hospital, Beijing, China.
Beijing Da Xue Xue Bao Yi Xue Ban. 2008 Dec 18;40(6):649-51.
We reported a rare case of protoplasmic astrocytoma presenting small muscle atrophy of the right hand as an initial sign. A 39-year-old male was admitted to hospital complaining of chronic muscle atrophy and subtle headache. Electromyography (EMG) showed brief small denervation and no signs of sensory-motor conduction impairment. CT and MRI revealed multiply expansive intracranial lesion in left hemisphere, which was highly suspected of cerebral echinococcus or Balo disease. The patient underwent surgical excision and pathological report was protoplasmic astrocytoma, with glial fibrillary acidic protein (GFAP, +++) of immunohistochemical method. We reviewed clinical features, radiological manifestations and pathology of protoplasmic astrocytoma with medical literature documents.