Lanza Alessandro, Laino Luigi, Rossiello Luigi, Perillo Letizia, Ermo Antonio Dell, Cirillo Nicola
Regional Center on Craniofacial Malformations-MRI, Section of Genetic Oral Diseases.
Open Dent J. 2008;2:73-7. doi: 10.2174/1874210600802010073. Epub 2008 Jun 3.
A wide range of diseases may present with radiographic features of osteolysis. Periapical inflammation, cysts and benign tumours, bone malignancies, all of these conditions may show bone resorption on radiograph. Features of the surrounding bone, margins of the lesion, and biological behaviour including tendency to infiltration and root resorption, may represent important criteria for distinguishing benign tumours from their malign counterpart, although the radiographic aspect of the lesion is not always predictive. Therefore a critical differential diagnosis has to be reached to choose the best management. Here, we report a case of giant cell tumour (GCT) whose radiological features by computed tomography (CT) suggested the presence of bone malignancy, whereas the evaluation of a routine OPT scan comforted us about the benign nature of the lesion. A brief review of the literature on such a benign but locally aggressive neoplasm is also provided.
多种疾病可能会呈现出骨质溶解的影像学特征。根尖周炎、囊肿和良性肿瘤、骨恶性肿瘤，所有这些情况在X线片上都可能显示骨质吸收。周围骨质的特征、病变边缘以及包括浸润倾向和牙根吸收在内的生物学行为，可能是区分良性肿瘤与其恶性对应物的重要标准，尽管病变的影像学表现并不总是具有预测性。因此，必须进行关键的鉴别诊断以选择最佳治疗方案。在此，我们报告一例骨巨细胞瘤（GCT），其计算机断层扫描（CT）的放射学特征提示存在骨恶性肿瘤，而常规口腔全景体层摄影（OPT）扫描的评估让我们确信该病变为良性。本文还对这种良性但具有局部侵袭性的肿瘤的相关文献进行了简要综述。
