新型隐球菌酚氧化酶的温度调节
Temperature regulation of the cryptococcal phenoloxidase.
作者信息
Jacobson E S, Emery H S
机构信息
Research Service, McGuire Veterans Affairs Medical Centre, Richmond, Virginia 23249.
出版信息
J Med Vet Mycol. 1991;29(2):121-4. doi: 10.1080/02681219180000201.
PMID:1908897
Abstract
Melanin formation at 37 degrees C has been proposed as a virulence factor in Cryptococcus neoformans. However, whereas catecholamine uptake is maintained at this temperature, phenoloxidase, which catalyses the oxidation of catecholamine to melanin, is severely decreased in most wild type strains cultivated at 37 degrees C.
摘要
在37摄氏度下黑色素的形成已被认为是新型隐球菌的一种毒力因子。然而，尽管在这个温度下儿茶酚胺的摄取得以维持，但在37摄氏度培养的大多数野生型菌株中，催化儿茶酚胺氧化为黑色素的酚氧化酶却严重减少。
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