Tolkunov B F
I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia.
Neurosci Behav Physiol. 2009 Jan;39(1):99-105. doi: 10.1007/s11055-008-9093-3. Epub 2008 Dec 17.
The spike activity of neurons with associative functions, studied as a neural correlate of behavior, constitutes an efferent spike flow which operates continuously throughout each of an animal's actions. However, research practice is dominated by methods based on the "stimulus-response" principle. Analysis from other points of view, directed to investigating the dynamics of neuron activity in monkeys during performance of a multistep behavioral program showed that differences in neuron activity of neurons during performance of different behavioral actions are not so much in terms of the numbers of cells responding or the activation of neurons specialized for the action concerned as in terms of changes in the composition of active neurons, with the formation of different combinations. As each combination of active neurons determines the distribution of efferent signals characteristic of this combination, these data suggest the existence of an addressing mechanism encoding efferent signals.
作为行为的神经关联物进行研究的具有联合功能的神经元的锋电位活动，构成了一种传出锋电位流，它在动物的每一个动作过程中持续运作。然而，研究实践主要由基于“刺激-反应”原则的方法主导。从其他角度进行分析，旨在研究猴子在执行多步骤行为程序过程中神经元活动的动态变化，结果表明，在执行不同行为动作时，神经元活动的差异与其说是在做出反应的细胞数量或专门针对相关动作的神经元的激活方面，不如说是在活跃神经元组成的变化方面，伴随着不同组合的形成。由于活跃神经元的每一种组合都决定了该组合特有的传出信号分布，这些数据表明存在一种编码传出信号的寻址机制。
