Mehrdad Jahanshahi, Sadeghi Y, Hosseini A, Naghdi N
Department of Anatomy, Gorgan University of Medical Sciences, Gorgan, Iran.
Pak J Biol Sci. 2007 Nov 1;10(21):3964-6. doi: 10.3923/pjbs.2007.3964.3966.
In this study with usage of morris water maze and reference memory technique, we used 10 male albino wistar rats. Five rats in control group and 5 rats in Reference memory group. After histological preparation, the slides were stained with PTAH staining for showing the Astrocytes. Present results showed significant difference in astrocytes number in CA1, CA2 and CA3 area of hippocampus between control and reference memory group. The number of astrocytes is increased in reference memory group. Then we divided the hippocampus to three parts: Anterior, middle and posterior and with compare of different area (CA1, CA2 and CA3) of hippocampus, we found that the increase of astrocytes number in posterior two-third of CA2 and CA3 is more than of it's number in the anterior one-third.
在这项使用莫里斯水迷宫和参考记忆技术的研究中,我们使用了10只雄性白化Wistar大鼠。对照组有5只大鼠,参考记忆组有5只大鼠。经过组织学制备后,玻片用磷钨酸苏木精(PTAH)染色以显示星形胶质细胞。目前的结果显示,对照组和参考记忆组在海马体CA1、CA2和CA3区域的星形胶质细胞数量存在显著差异。参考记忆组中星形胶质细胞的数量增加。然后我们将海马体分为三个部分:前部、中部和后部,通过比较海马体不同区域(CA1、CA2和CA3),我们发现CA2和CA3后三分之二区域的星形胶质细胞数量增加比前三分之一区域更多。