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血液透析导管肝素泄漏导致大出血,最终导致移植排斥和死亡。

Heparin leak from a hemodialysis catheter causing major bleeding, ultimately leading to transplant rejection and death.

作者信息

Dreyer Gavin, Lawton Paul, Jose Matthew

机构信息

Department of Nephrology, Royal London Hospital, London, UK.

出版信息

Hemodial Int. 2008 Oct;12(4):431-3. doi: 10.1111/j.1542-4758.2008.00306.x.

DOI:10.1111/j.1542-4758.2008.00306.x
PMID:19090865
Abstract

Leakage of hemodialysis catheter-locking solutions into the circulation has been reported in in vitro and in vivo studies, although there have been few reports of serious clinical adverse events. We describe a case of heparin leak from a hemodialysis catheter, which caused significant clinical bleeding requiring multiple transfusions and may have ultimately been responsible for the patient's death after transplantation.

摘要

在体外和体内研究中均有血液透析导管封管溶液漏入循环系统的报道,尽管关于严重临床不良事件的报道较少。我们描述了一例血液透析导管肝素渗漏的病例,该渗漏导致了严重的临床出血,需要多次输血,并且可能最终导致了患者移植后的死亡。

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Heparin leak from a hemodialysis catheter causing major bleeding, ultimately leading to transplant rejection and death.血液透析导管肝素泄漏导致大出血,最终导致移植排斥和死亡。
Hemodial Int. 2008 Oct;12(4):431-3. doi: 10.1111/j.1542-4758.2008.00306.x.
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引用本文的文献

1
Heparin compared with normal saline to maintain patency of permanent double lumen hemodialysis catheters: A randomized controlled trial.肝素与生理盐水用于维持永久性双腔血液透析导管通畅性的比较:一项随机对照试验。
Adv Biomed Res. 2014 May 28;3:121. doi: 10.4103/2277-9175.133192. eCollection 2014.