Bhandari S, Armitage J, Chintu M, Chinnappa S, Kendrew P
Department of Renal Medicine, Hull and East Yorkshire Hospitals NHS Trust, Kingston upon Hull, UK.
J Ren Care. 2008 Dec;34(4):213-7. doi: 10.1111/j.1755-6686.2008.00040.x.
Medication allergies are potentially important but usually poorly documented in patient medical records. Allergy awareness by clinical staff may be low in the haemodialysis population despite their regular attendance for treatment sessions. A cross-sectional study of 25 patients in a satellite unit was performed. All known allergies were not documented in 36% of patients despite the patients being known to the renal service for more than five years. 81% of allergies were medication allergies. The rest were due to topical agents. 57% (affecting 8 patients) of the medication allergies related to antibiotics (especially penicillin). Four patients had multiple antibiotic allergies. The nature and severity of these allergies was not well documented. This study demonstrates that despite being under long-term care there remains incomplete information, which is vital for optimal safe practice. Without such information, the potential for adverse events and anaphylaxis is significant in a population that is exposed to numerous pharmaceutical agents and are frequently prescribed antibiotics. Medication histories should be comprehensively re-evaluated regularly and prescribing should not occur unless the allergy box is completed.
药物过敏可能很重要，但在患者病历中通常记录不完整。尽管血液透析患者定期接受治疗，但临床工作人员对过敏的认知度在这一群体中可能较低。对一个卫星透析单元的25名患者进行了一项横断面研究。尽管这些患者已被肾脏服务机构知晓超过五年，但仍有36%的患者所有已知过敏情况未被记录。81%的过敏是药物过敏。其余的是由局部用药引起的。57%（涉及8名患者）的药物过敏与抗生素（尤其是青霉素）有关。有4名患者对多种抗生素过敏。这些过敏的性质和严重程度记录不完善。这项研究表明，尽管患者接受长期护理，但信息仍不完整，而这些信息对于最佳安全操作至关重要。没有这些信息，在一个接触多种药剂且经常使用抗生素的人群中，发生不良事件和过敏反应的可能性很大。应定期全面重新评估用药史，除非过敏情况栏已填写完整，否则不应开药。
