微小转移乳腺癌的假定生长特征。
Putative growth characteristics of micrometastatic breast cancer.
作者信息
Chambers Ann F, Goss Paul E
出版信息
Breast Cancer Res. 2008;10(6):114. doi: 10.1186/bcr2197. Epub 2008 Nov 27.
Abstract
The fate of cells that disseminate from a primary breast tumour remains poorly understood. Studies of the kinetics of recurrence in breast cancer patients are raising important questions about the biology of the metastatic process. Where do tumour cells reside once they leave the primary tumour, and what factors influence their dormancy and recurrent growth? Clinical data analyses are leading to hypotheses about the biology of metastasis, dormancy and recurrence. A combined clinical and experimental approach to testing these hypotheses will help to clarify this important issue in breast cancer biology and patient care.
摘要
从原发性乳腺肿瘤扩散的细胞命运仍知之甚少。对乳腺癌患者复发动力学的研究提出了有关转移过程生物学的重要问题。肿瘤细胞一旦离开原发性肿瘤后会驻留在何处，以及哪些因素会影响它们的休眠和复发生长？临床数据分析正在催生有关转移、休眠和复发生物学的假说。采用临床与实验相结合的方法来检验这些假说，将有助于阐明乳腺癌生物学和患者护理方面的这一重要问题。
相似文献
1
Putative growth characteristics of micrometastatic breast cancer.微小转移乳腺癌的假定生长特征。
Breast Cancer Res. 2008;10(6):114. doi: 10.1186/bcr2197. Epub 2008 Nov 27.
2
Tumour dormancy: findings and hypotheses from clinical research on breast cancer.肿瘤休眠：乳腺癌临床研究的发现与假说
Semin Cancer Biol. 2001 Aug;11(4):297-306. doi: 10.1006/scbi.2001.0385.
3
Tumor dormancy and cancer stem cells: implications for the biology and treatment of breast cancer metastasis.肿瘤休眠与癌症干细胞：对乳腺癌转移生物学及治疗的启示
Breast Dis. 2006;26:87-98. doi: 10.3233/bd-2007-26108.
4
Exploiting Mouse Models to Recapitulate Clinical Tumor Dormancy and Recurrence in Breast Cancer.利用小鼠模型重现乳腺癌临床肿瘤休眠和复发。
Endocrinology. 2022 Jun 1;163(6). doi: 10.1210/endocr/bqac055.
5
Mechanisms driving local breast cancer recurrence in a model of breast-conserving surgery.保乳手术模型中驱动局部乳腺癌复发的机制
Ann Surg Oncol. 2008 Oct;15(10):2954-64. doi: 10.1245/s10434-008-0037-5. Epub 2008 Jul 12.
6
Proposal for a new model of breast cancer metastatic development.乳腺癌转移发展新模型的提议。
Ann Oncol. 1997 Nov;8(11):1075-80. doi: 10.1023/a:1008263116022.
7
How can we integrate the biology of breast cancer cell dormancy into clinical practice?我们如何将乳腺癌细胞休眠的生物学特性融入临床实践？
Cancer Cell. 2024 Jul 8;42(7):1147-1151. doi: 10.1016/j.ccell.2024.05.023. Epub 2024 Jun 20.
8
Host-Related Factors in the Interplay among Inflammation, Immunity and Dormancy in Breast Cancer Recurrence and Prognosis: An Overview for Clinicians.宿主相关因素在乳腺癌复发和预后中的炎症、免疫和休眠相互作用中的作用：临床医生的概述。
Int J Mol Sci. 2023 Mar 4;24(5):4974. doi: 10.3390/ijms24054974.
9
Breast cancer recurrence dynamics following adjuvant CMF is consistent with tumor dormancy and mastectomy-driven acceleration of the metastatic process.辅助性CMF治疗后乳腺癌复发动态与肿瘤休眠及乳房切除术驱动的转移过程加速相一致。
Ann Oncol. 2005 Sep;16(9):1449-57. doi: 10.1093/annonc/mdi280. Epub 2005 Jun 14.
10
Concomitant resistance and early-breast cancer: should we change treatment strategies?伴随性耐药与早期乳腺癌：我们是否应该改变治疗策略？
Cancer Metastasis Rev. 2014 Mar;33(1):271-83. doi: 10.1007/s10555-013-9449-1.
引用本文的文献
1
A signature of epithelial-mesenchymal plasticity and stromal activation in primary tumor modulates late recurrence in breast cancer independent of disease subtype.原发性肿瘤中上皮-间质可塑性和基质激活的特征独立于疾病亚型调节乳腺癌的晚期复发。
Breast Cancer Res. 2014 Jul 25;16(4):407. doi: 10.1186/s13058-014-0407-9.
2
Differences in metastatic patterns in relation to time between primary surgery and first relapse from breast cancer suggest synchronized growth of dormant micrometastases.乳腺癌原发手术与首次复发之间转移模式随时间的差异提示休眠微转移灶的同步生长。
Breast Cancer Res Treat. 2014 Aug;146(3):627-36. doi: 10.1007/s10549-014-3057-9. Epub 2014 Jul 20.
3
Breast cancer as a systemic disease: a view of metastasis.乳腺癌作为一种全身性疾病：转移观点。
J Intern Med. 2013 Aug;274(2):113-26. doi: 10.1111/joim.12084.
4
What can be learnt about disease progression in breast cancer dormancy from relapse data?从复发数据中可以了解到乳腺癌休眠中疾病进展的哪些信息？
PLoS One. 2013 May 6;8(5):e62320. doi: 10.1371/journal.pone.0062320. Print 2013.
5
Expression profiling after induction of demethylation in MCF-7 breast cancer cells identifies involvement of TNF-α mediated cancer pathways.MCF-7 乳腺癌细胞去甲基化诱导后表达谱分析鉴定 TNF-α 介导的癌症通路的参与。
Mol Cells. 2012 Feb;33(2):127-33. doi: 10.1007/s10059-012-2182-8. Epub 2012 Jan 2.
6
Genomic analysis of circulating cell-free DNA infers breast cancer dormancy.循环游离 DNA 的基因组分析推断乳腺癌休眠。
Genome Res. 2012 Feb;22(2):220-31. doi: 10.1101/gr.123497.111. Epub 2011 Oct 11.
本文引用的文献
1
Recurrence dynamics does not depend on the recurrence site.复发动态不取决于复发部位。
Breast Cancer Res. 2008;10(5):R83. doi: 10.1186/bcr2152. Epub 2008 Oct 9.
2
Review: Biological relevance of disseminated tumor cells in cancer patients.综述：癌症患者中播散肿瘤细胞的生物学相关性
Int J Cancer. 2008 Nov 1;123(9):1991-2006. doi: 10.1002/ijc.23825.
3
Cancer stem cells: implications for the progression and treatment of metastatic disease.癌症干细胞：对转移性疾病进展和治疗的影响
J Cell Mol Med. 2008 Apr;12(2):374-90. doi: 10.1111/j.1582-4934.2007.00211.x. Epub 2007 Dec 20.
4
TEACH: Tykerb evaluation after chemotherapy.TEACH：化疗后对拉帕替尼的评估。
Clin Breast Cancer. 2007 Feb;7(6):489-92. doi: 10.3816/CBC.2007.n.007.
5
Dormant cancer cells retrieved from metastasis-free organs regain tumorigenic and metastatic potency.从无转移器官中获取的休眠癌细胞恢复了致瘤性和转移能力。
Am J Pathol. 2006 Aug;169(2):673-81. doi: 10.2353/ajpath.2006.060053.
6
Improvement of breast cancer relapse prediction in high risk intervals using artificial neural networks.使用人工神经网络改善高危间期乳腺癌复发预测
Breast Cancer Res Treat. 2005 Dec;94(3):265-72. doi: 10.1007/s10549-005-9013-y.
7
Randomized trial of letrozole following tamoxifen as extended adjuvant therapy in receptor-positive breast cancer: updated findings from NCIC CTG MA.17.来曲唑继他莫昔芬之后作为受体阳性乳腺癌延长辅助治疗的随机试验：NCIC CTG MA.17的最新研究结果
J Natl Cancer Inst. 2005 Sep 7;97(17):1262-71. doi: 10.1093/jnci/dji250.
8
Hazard rates of recurrence following diagnosis of primary breast cancer.原发性乳腺癌诊断后的复发风险率。
Breast Cancer Res Treat. 2005 Jan;89(2):173-8. doi: 10.1007/s10549-004-1722-0.
9
Ineffectiveness of doxorubicin treatment on solitary dormant mammary carcinoma cells or late-developing metastases.阿霉素治疗对孤立性休眠乳腺癌细胞或晚期转移灶无效。
Breast Cancer Res Treat. 2003 Dec;82(3):199-206. doi: 10.1023/B:BREA.0000004377.12288.3c.
10
A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer.来曲唑用于早期乳腺癌患者他莫昔芬治疗五年后的绝经后女性的一项随机试验。
N Engl J Med. 2003 Nov 6;349(19):1793-802. doi: 10.1056/NEJMoa032312. Epub 2003 Oct 9.
Zotero 插件