白内障手术后，ReSTOR人工晶状体与单焦点人工晶状体植入术相比，矫正及未矫正的近视力和远视力：一项汇总分析。

Corrected and uncorrected near and distance vision with ReSTOR compared to monofocal intraocular lens implantation after cataract surgery: a pooled analysis.

作者信息

Cochener Béatrice, Arnould Benoit, Viala Muriel, Roborel de Climens Aude, Berdeaux Gilles

机构信息

Centre Hospitalier Universitaire de Brest, France.

出版信息

Ophthalmologica. 2009;223(2):128-35. doi: 10.1159/000183845. Epub 2008 Dec 18.

DOI:10.1159/000183845

PMID:19092283

Abstract

BACKGROUND/AIM: To evaluate distance and near vision-related benefit after implantation of ReSTOR multifocal intraocular lenses (IOLs) following cataract surgery.

METHODS

Two prospective open-labeled nonrandomized studies were pooled. Patients' perception of benefit was assessed with the TyPE, administered at baseline and after each eye surgery.

RESULTS

A total of 499 patients received ReSTOR IOLs, and 173 received monofocal IOLs. The distance vision of monofocal and ReSTOR patients improved equally with and without glasses. A greater improvement in near vision without glasses was reported by ReSTOR-implanted patients as early as after the 1st eye surgery (p < 0.0001). More ReSTOR patients than monofocal patients reported independence from glasses after the 1st eye surgery (64 vs. 52%; p = 0.0002). This difference had increased after the 2nd eye surgery (85 vs. 51%; p < 0.0001).

CONCLUSIONS

The improvement in near vision without glasses was significantly more evident in ReSTOR patients, allowing the majority of them to be free of glasses.

摘要

背景/目的：评估白内障手术后植入ReSTOR多焦点人工晶状体（IOL）后与远视力和近视力相关的益处。

方法

汇总两项前瞻性开放标签非随机研究。使用TyPE在基线时以及每只眼手术后评估患者对益处的感知。

结果

共有499例患者接受了ReSTOR人工晶状体，173例接受了单焦点人工晶状体。单焦点和ReSTOR患者的远视力在戴眼镜和不戴眼镜的情况下均有同等改善。早在第一只眼手术后，植入ReSTOR人工晶状体的患者报告不戴眼镜时近视力有更大改善（p<0.0001）。第一只眼手术后，报告无需眼镜的ReSTOR患者比单焦点患者更多（64%对52%；p = 0.0002）。第二只眼手术后这种差异有所增加（85%对51%；p<0.0001）。