Pepose Jay S, Qazi Mujtaba A, Davies James, Doane John F, Loden James C, Sivalingham Varunan, Mahmoud Ashraf M
Pepose Vision Institute, St Louis, Missouri 63017, USA.
Am J Ophthalmol. 2007 Sep;144(3):347-357. doi: 10.1016/j.ajo.2007.05.036. Epub 2007 Jul 25.
To compare the visual performance of patients with bilateral vs combination Crystalens, ReZoom, and ReSTOR intraocular lens (IOLs) implants.
Prospective, nonrandomized study.
Forty-nine patients were implanted with bilateral Crystalens (Eyeonics, Aliso Viejo, California, USA), ReSTOR (Alcon Laboratories, Fort Worth, Texas, USA), and ReZoom (American Medical Optics, Santa Clara, California, USA) or combined Crystalens and ReSTOR or Crystalens and ReZoom IOLs after phacoemulsification. Monocular and binocular testing four to six months after surgery included uncorrected and best-spectacle corrected visual acuity at distance, intermediate, and near vision; mesopic contrast sensitivity function with and without glare; and quality-of-life and vision surveys six months after surgery.
Monocular testing showed that eyes with Crystalens accommodating IOL had statistically better best-spectacle corrected distance, uncorrected and distance-corrected intermediate, and best-corrected near vision. Eyes with the ReSTOR multifocal IOL had better uncorrected near vision, required the lowest reading add, and had the lowest uncorrected and distance-corrected intermediate vision. Monocular mesopic contrast sensitivity with and without glare was better with the Crystalens IOL vs either multifocal IOL at specific spatial frequencies. The binocular subjective quality of vision and quality of life questionnaires were favorable for the bilateral Crystalens group.
Any combination of Crystalens in one or both eyes was better for intermediate vision. Any combination of ReSTOR in one or both eyes was better for near vision. The Crystalens and ReSTOR combination had better mean intermediate and near vision overall. A multifocal IOL in one or both eyes was associated with lower contrast sensitivity and more subjective reports of photic phenomena. The accommodating and multifocal IOL combinations elicited less night glare symptoms than in patients with either bilateral multifocal IOL, but more than with bilateral Crystalens implantation.
比较双侧植入与联合植入Crystalens、ReZoom和ReSTOR人工晶状体(IOL)的患者的视觉表现。
前瞻性、非随机研究。
49例患者在白内障超声乳化术后植入双侧Crystalens(美国加利福尼亚州阿利索维耶荷市Eyeonics公司)、ReSTOR(美国得克萨斯州沃思堡市爱尔康实验室公司)和ReZoom(美国加利福尼亚州圣克拉拉市美国医学光学公司)IOL,或联合植入Crystalens和ReSTOR或Crystalens和ReZoom IOL。术后4至6个月的单眼和双眼测试包括远、中、近视力的未矫正和最佳眼镜矫正视力;有无眩光情况下的中视对比敏感度函数;以及术后6个月的生活质量和视力调查。
单眼测试显示,植入Crystalens可调节IOL的眼睛在最佳眼镜矫正远视力、未矫正和远矫正中视力以及最佳矫正近视力方面在统计学上具有更好的表现。植入ReSTOR多焦点IOL的眼睛具有更好的未矫正近视力,所需的阅读附加度数最低,且未矫正和远矫正中视力最低。在特定空间频率下,与任何一种多焦点IOL相比,Crystalens IOL在有无眩光情况下的单眼中视对比敏感度更好。双眼主观视觉质量和生活质量问卷对双侧Crystalens组有利。
一只或两只眼睛植入Crystalens的任何组合对中视力更好。一只或两只眼睛植入ReSTOR的任何组合对近视力更好。总体而言,Crystalens和ReSTOR组合的中视力和近视力更好。一只或两只眼睛植入多焦点IOL与较低的对比敏感度以及更多关于光现象的主观报告相关。与双侧植入多焦点IOL的患者相比,可调节和多焦点IOL组合引起的夜间眩光症状更少,但比双侧植入Crystalens的患者更多。