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[卒中单元实施“不要复苏”医嘱前后]

[Before and after implementation of do-not-resuscitate orders in a stroke unit].

作者信息

Mjåset Christer, Gulbrandsen Pål, Rønning Ole Morten, Thommessen Bente

机构信息

Nevrologisk avdeling Akershus universitetssykehus 1478 Lørenskog.

出版信息

Tidsskr Nor Laegeforen. 2008 Dec 18;128(24):2819-22.

Abstract

BACKGROUND

In Norway, few studies have been done to map the extent of do-not-resuscitate (DNR) orders and the consequence for patients (treatment and outcome).

MATERIAL AND METHODS

All patients with DNR orders, referred to the stroke unit of Akershus University Hospital during the year 2005, were identified and data on treatment and outcome were recorded.

RESULTS

A DNR order was found for 79 of 855 (9 %) patients (mean age 80 years [SD 9]). Reasons for referral to hospital were: cerebral infarction (49 [62 %] patients), intracerebral haemorrhage (28 [35 %] patients), and other diseases (2 [3 %] patients). Mean NIH Stroke Scale was 19 (SD 6) (scale 0 - 42; 0 in score meaning no stroke related symptoms). Hospital mortality was 39/79 (49 %). Apart from once, all decisions regarding withholding and/or withdrawing life-sustaining treatment were taken in the aftermath of a DNR order. For 43 patients (54 %), treatment was limited in some way and hospital mortality for this group was 27/43 (63 %). Mortality was 12/36 (33 %) for those who had full treatment. 45 patients (57 %) with a DNR order had a bacterial infection and 32 of them were treated with antibiotics (71 %).

INTERPRETATION

Patients with DNR orders were old and had had severe stroke. Treatment was rarely withheld despite high morbidity and mortality among the patients.

摘要

背景

在挪威,针对“不要复苏”(DNR)医嘱的范围及其对患者的影响(治疗和结局)所开展的研究很少。

材料与方法

确定了2005年期间转诊至阿克什胡斯大学医院卒中单元的所有开具DNR医嘱的患者,并记录了治疗及结局数据。

结果

在855例患者中有79例(9%)开具了DNR医嘱(平均年龄80岁[标准差9])。转诊至医院的原因包括:脑梗死(49例[62%])、脑出血(28例[35%])以及其他疾病(2例[3%])。美国国立卫生院卒中量表(NIHSS)平均评分为19分(标准差6)(量表范围0 - 42分;分数为0表示无卒中相关症状)。医院死亡率为39/79(49%)。除1次外,所有关于停止和/或撤销维持生命治疗的决定均在开具DNR医嘱之后做出。对于43例患者(54%),治疗在某种程度上受到限制,该组患者的医院死亡率为27/43(63%)。接受全面治疗的患者死亡率为12/36(33%)。45例(57%)开具DNR医嘱的患者发生了细菌感染,其中32例接受了抗生素治疗(71%)。

解读

开具DNR医嘱的患者年龄较大且患有严重卒中。尽管患者的发病率和死亡率较高,但很少停止治疗。

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