Kim Hui-Jung, Hong Yun-Kyung, Yoo Wan-Hee
Division of Rheumatology, Department of Internal Medicine, Chonbuk National University Medical School and Research Institute of Clinical Medicine, #634-18, Geum-Am Dong, Deock-Jin Gu, Jeonju, Jeononbuk, 561-712, South Korea.
Rheumatol Int. 2009 Jul;29(9):1101-4. doi: 10.1007/s00296-008-0822-2. Epub 2008 Dec 18.
We report a rare case of patient with dermatomyositis (DM) who developed spontaneous pneumomediastinum (PnM) and subcutaneous emphysema. She was successfully treated with oral prednisolone and cyclosporine A (CsA). We reviewed the cases of PnM in patients with DM treated with CsA. A review of four previously reported cases revealed that treatment with systemic glucocorticoid and CsA was effective for the DM and PnM. We indicate that initial and early treatment of the patients with DM and PnM with CsA enabled rapid tapering of the dose of glucocorticoid and improved the disease.
我们报告了一例罕见的皮肌炎（DM）患者，该患者出现了自发性纵隔气肿（PnM）和皮下气肿。她通过口服泼尼松龙和环孢素A（CsA）成功治愈。我们回顾了使用CsA治疗的DM患者发生PnM的病例。对之前报道的4例病例的回顾显示，全身糖皮质激素和CsA治疗对DM和PnM有效。我们指出，对DM和PnM患者早期使用CsA进行初始治疗能够迅速减少糖皮质激素的用量并改善病情。
