Tian Yu-mei, Zhou Dan, Zhang Wei, Cheng Cun-gui
Zhejiang Key Laboratory for Reactive Chemistry on Solid Surfaces, Department of Chemistry, Zhejiang Normal University, Jinhua 321004, China.
Guang Pu Xue Yu Guang Pu Fen Xi. 2008 Sep;28(9):2192-5.
Traditional Chinese medicine materials (TCM) contained abundant trace elements needed in human body. Mixed acid (HNO3:HClO4) was added into samples treated by microwave digestion, and a systematic study was carried out by selection of the most appropriate working conditions and optimization of the sample mass. Some inorganic elements in 5 kinds of radix curcumae (Curcuma wenyujin Y. H. Chen et C. Ling, Curcuma longa L., Curcuma kwangsiensis S. G. Lee et C. F. Liang, Curcuma phaeocaulis Val. and Curcuma chuanyujin C. K Hsieh et H. Zhang) necessary to lives were determined by flames atomic absorption spectrometry (AAS). Elements, such as K, Ca, Na, Mg, Zn, Fe, Cu and Mn were detected. The results show that there are similar elements in the five kinds of radix curcumae, while differences only exist in a few elements contents. The correlative analysis of trace elements in samples was carried out by cluster analysis of the 4 kinds of radix curcumae (Curcuma wenyujin Y. H. Chen et C. Ling, Curcuma longa L., Curcuma kwangsiensis S. G. Lee et C. F. Liang and Curcuma phaeocaulis Val. ) in codex populations in a cluster, different from the unofficial sample (Curcuma chuanyujin C. K. Hsieh et H. Zhang). The cluster analysis results are consistent with the morphological characteristics of the traditional taxonomy results. The results showed that the analytic method is advisable. This paper provides scientific basis for deeply studing the relation between trace elements and drug effect of radix curcumae.
中药材含有丰富的人体所需微量元素。采用微波消解处理样品,并加入混合酸(硝酸:高氯酸),通过选择最合适的工作条件和优化样品质量进行了系统研究。采用火焰原子吸收光谱法(AAS)测定了5种姜黄属药材(温郁金、姜黄、广西莪术、蓬莪术和川郁金)中一些生命必需的无机元素。检测了钾、钙、钠、镁、锌、铁、铜和锰等元素。结果表明,5种姜黄属药材中存在相似的元素,仅少数元素含量存在差异。通过对《中国药典》收载的4种姜黄属药材(温郁金、姜黄、广西莪术和蓬莪术)进行聚类分析,与非法定样品(川郁金)进行样品中微量元素的相关性分析。聚类分析结果与传统分类学的形态学特征结果一致。结果表明该分析方法可行。本文为深入研究姜黄属药材微量元素与药效之间的关系提供了科学依据。