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巴伐尔德氏青光眼植入物在玻璃体手术后难治性青光眼治疗中的应用。

Baerveldt glaucoma implants in the management of refractory glaucoma after vitreous surgery.

机构信息

Department of Ophthalmology, Service of Vitreoretinal Surgery, University Hospital Ghent, Belgium.

出版信息

Acta Ophthalmol. 2010 Feb;88(1):75-9. doi: 10.1111/j.1755-3768.2008.01428.x. Epub 2009 Dec 16.

Abstract

PURPOSE

To examine the effectiveness and safety of Baerveldt glaucoma implants in eyes with refractory glaucoma following vitrectomy.

METHODS

We performed a retrospective study of a non-comparative case series of 30 eyes of 30 patients who had undergone the implantation of a Baerveldt glaucoma device. All eyes (30/30) had a minimum follow-up of 6 months, and 16/30 (53%) had a follow-up of 24 months. Surgical success was defined as intraocular pressure (IOP) < 22 mmHg on the last two follow-up visits with or without glaucoma medication and a decrease in IOP of at least 20% compared to preoperative values with or without glaucoma medication.

RESULTS

The mean IOP before implantation of a Baerveldt glaucoma device was 30 mmHg [+/- 11.4 mmHg standard deviation (SD)] with maximally tolerated medical therapy. Six months after implantation of the Baerveldt glaucoma device, the mean IOP was 17.3 mmHg (+/- 6.7 mmHg SD) and the mean number of glaucoma medications had gone down from 3.0 (+/- 0.4 SD) to 0.3 (+/- 0.3 SD). Successful outcomes were found in 24 eyes (80%). Small complications occurred in six eyes (20%): transient postoperative hypotony (17%) and tube retraction (3%). Larger complications occurred in another six eyes (20%): corneal decompensation requiring keratoplasty (7%), suprachoroidal haemorrhage (3%) and persistently high IOP (10%).

CONCLUSION

Baerveldt glaucoma devices are a valid treatment option in eyes with refractory glaucoma after vitreous surgery, although failure occurred in 20% of our patients. Transient complications occurred in 20% and severe complications in another 20%.

摘要

目的

探讨巴伐利亚青光眼植入物在玻璃体切除术后难治性青光眼眼中的有效性和安全性。

方法

我们对 30 例 30 只眼进行了非对照病例系列回顾性研究,这些患者均接受了巴伐利亚青光眼装置植入术。所有眼(30/30)的随访时间均至少为 6 个月,16/30(53%)的随访时间为 24 个月。手术成功定义为最后两次随访时眼压(IOP)<22mmHg,无需药物治疗或仅需药物治疗,且与术前相比,IOP 下降至少 20%,药物治疗或不治疗。

结果

植入巴伐利亚青光眼装置前,平均眼压为 30mmHg[+/-11.4mmHg标准差(SD)],最大耐受药物治疗。植入巴伐利亚青光眼装置 6 个月后,平均眼压为 17.3mmHg[+/-6.7mmHgSD],平均降眼压药物数量从 3.0[+/-0.4SD]降至 0.3[+/-0.3SD]。24 只眼(80%)取得了成功的结果。6 只眼(20%)出现小并发症:一过性术后低眼压(17%)和引流管回缩(3%)。另外 6 只眼(20%)出现较大并发症:需要角膜移植的角膜失代偿(7%)、脉络膜上腔出血(3%)和持续高眼压(10%)。

结论

巴伐利亚青光眼装置是玻璃体切除术后难治性青光眼眼的有效治疗选择,尽管我们的患者中有 20%失败。20%的患者出现短暂并发症,20%的患者出现严重并发症。

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