Zhang Li, Wang Jun, Zhang Cheng-shu, Zhou Ping-hui, Qian Jing-yu, Li Xu-wen, Ge Shu-xing
Department of Plastic and Reconstructive Surgery, the First Affiliated Hospital of Bengbu Medical College, Bengbu 233004, China.
Zhonghua Wai Ke Za Zhi. 2008 Oct 1;46(19):1472-4.
To investigate the safety and efficacy of sonographically guided percutaneous intralesional sclerotherapy for peripheral venous malformations.
From March 2004 to October 2007, 32 patients with venous malformations of soft tissues were treated with sonographically guided intralesional sclerotherapy. The malformed venous space was identified intraoperatively by duplex scanning, the gauge 7 needle was inserted into this venous space under real-time ultrasound visualization, and sclerosants were infused in the space gently. Absolute alcohol and bleomycin acted as sclerosants here, combined the two (for type I malformation) or bleomycin only (for type II malformation). The treatment could be repeated if the lesion was not cured in 3 weeks. All patients were followed up for 6 months to 2 years.
Of the group, each patient received 1 - 6 times of the therapy (mean, 3 times). Twenty-seven patients achieved a complete response, and 5 achieved partial response. No major complications occurred.
Sonographically guided percutaneous intralesional sclerotherapy for peripheral venous malformation is a simple, effective, safe therapy with minimal invasion, lower morbidity rate, and can be repeated.
探讨超声引导下经皮病灶内硬化治疗外周静脉畸形的安全性和有效性。
2004年3月至2007年10月，对32例软组织静脉畸形患者采用超声引导下病灶内硬化治疗。术中通过双功扫描识别畸形静脉腔，在实时超声引导下将7号针插入该静脉腔，然后将硬化剂缓慢注入腔内。无水乙醇和博来霉素作为硬化剂，两者联合使用（用于I型畸形）或仅使用博来霉素（用于II型畸形）。如果3周内病变未治愈，可重复治疗。所有患者随访6个月至2年。
该组患者每人接受1 - 6次治疗（平均3次）。27例患者完全缓解，5例部分缓解。未发生严重并发症。
超声引导下经皮病灶内硬化治疗外周静脉畸形是一种简单、有效、安全的治疗方法，具有微创、发病率低且可重复的特点。
