1998年至2005年期间，HIV感染患者肝脏相关住院率及住院死亡率的变化。

Changes in liver-related hospital admissions and hospital mortality among HIV-infected patients (1998 to 2005).

作者信息

del Valle José, Macías Juan, Mira José Antonio, García-García José Angel, Gómez-Mateos Jesús, Pineda Juan Antonio

机构信息

Unidad de Enfermedades Infecciosas, Hospital Universitario de Valme, Seville, Spain.

出版信息

Enferm Infecc Microbiol Clin. 2008 Oct;26(8):500-1.

PMID:19094863

Abstract

Liver-related disease has increased as a cause of hospitalization and in-hospital death in HIV-infected patients since the introduction of highly active antiretroviral therapy (HAART). Better clinical management of these diseases may contribute to decreasing their incidence. Admissions due to liver-related disease in HIV-infected patients in our institution increased from 2.9% in 1998-1999 to 11.3% in 2004-2005 (P = 0.001). In-hospital deaths due to this cause increased from 2.7% in 1998-1999 to 26% in 2002-2003 (P = 0.02), with a subsequent decrease to 22% in 2004-2005. Hospitalization of HIV-infected patients for liver-related disease continues to increase, whereas the rate of in-hospital deaths from this cause appears to have changed since 2003.

摘要

自高效抗逆转录病毒疗法（HAART）引入以来，肝脏相关疾病已成为导致HIV感染患者住院和院内死亡的一个日益常见的原因。对这些疾病进行更好的临床管理可能有助于降低其发病率。在我们机构中，HIV感染患者因肝脏相关疾病而住院的比例从1998 - 1999年的2.9%上升至2004 - 2005年的11.3%（P = 0.001）。因该原因导致的院内死亡比例从1998 - 1999年的2.7%上升至2002 - 2003年的26%（P = 0.02）随后在2004 - 2005年降至22%。HIV感染患者因肝脏相关疾病而住院的情况持续增加，然而自2003年以来，因该原因导致的院内死亡率似乎已有所变化。