Chapurlat Roland
Université de Lyon, Hôpital E. Herriot, France.
J Soc Biol. 2008;202(4):251-5. doi: 10.1051/jbio:2008033. Epub 2008 Dec 19.
Osteoporosis leads to fragility fractures. Fracture incidence increases after the menopause among women and with age in both genders. More than 40 % of women will sustain at least one fragility fracture after the age of 50. Many risk factors have been described, including age, familial history of fracture, low bone mineral density, personal history of fracture, smoking and low body mass index. Fracture incidence is increasing worldwide, owing to population aging. Hip and vertebral fractures are associated with increased mortality and morbidity. Costs related to fragility fractures represent a significant burden for health care systems.
骨质疏松症会导致脆性骨折。绝经后女性的骨折发生率会增加，且无论男女，骨折发生率都会随年龄增长而上升。超过40%的女性在50岁之后至少会发生一次脆性骨折。已描述了许多风险因素，包括年龄、骨折家族史、低骨密度、个人骨折史、吸烟和低体重指数。由于人口老龄化，全球骨折发生率正在上升。髋部和椎体骨折与死亡率和发病率增加相关。脆性骨折相关的费用对医疗保健系统而言是一项重大负担。
