睾酮在精子发生过程中的作用分子机制。
Molecular mechanisms of testosterone action in spermatogenesis.
作者信息
Walker William H
机构信息
Department of Cell Biology and Physiology and the Center for Research in Reproductive Physiology, Magee Women's Research Institute, University of Pittsburgh, Pittsburgh, PA 15261, United States.
出版信息
Steroids. 2009 Jul;74(7):602-7. doi: 10.1016/j.steroids.2008.11.017. Epub 2008 Nov 27.
Testosterone is required for the maturation of male germ cells, the production of sperm and thus male fertility. However, the mechanisms by which testosterone regulates spermatogenic processes have not been well defined. In this review, classical and non-classical pathways of testosterone signaling in the Sertoli cells of the testis are discussed in relation to testosterone-regulated processes that are required for spermatogenesis.
睾酮是男性生殖细胞成熟、精子产生以及男性生育能力所必需的。然而，睾酮调节生精过程的机制尚未完全明确。在本综述中，我们讨论了睾丸支持细胞中睾酮信号传导的经典和非经典途径，以及与精子发生所需的睾酮调节过程的关系。
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