Wu Yue, Shatapathy Chetan C, Minger Stephen L
Stem Cell Biology Laboratory, Wolfson Centre for Age-Related Diseases King's College London, London, UK.
Methods Mol Biol. 2009;481:181-92. doi: 10.1007/978-1-59745-201-4_15.
Hepatocyte transplantation has recently become an efficient clinical method in the treatment of patients with metabolic liver diseases. The shortage of donor cells remains an obstacle to treat more patients. Foetal liver tissues may therefore be useful as an alternative source of generating functional hepatocytes after in vitro culture and maturation.
肝细胞移植最近已成为治疗代谢性肝病患者的一种有效临床方法。供体细胞的短缺仍然是治疗更多患者的障碍。因此，胎儿肝脏组织可能作为体外培养和成熟后产生功能性肝细胞的替代来源。
