Niang S O, Dieng M T, Kane A, Diop S N, Ndiaye B
1- Service de Dermatologie, Hôpital Aristide Le Dantec, BP 3001 Dakar 2 - Service de Medecine Interne. H6pital Abass Ndao.
Dakar Med. 2007;52(3):216-22.
Sarcoidosis cases had been rarely reported in Senegal in spite of the high frequency of sarcoidosis in black people. The purpose of this work was to determine the epidemiological, clinical and evaluative profile of sarcoidosis in Dakar.
We performed a multicentric retrospective trial in order to characterise sarcoidosis cases in Senegal from 1968 to 2004.
Twenty cases (21 females and 9 men) were observed. The average age was 40 years. Duration before first medical attention was up to one year in 20 cases. Ten patients received an anti tuberculosis treatment before sarcoidosis diagnosis. Sarcoidosis was a systemic disease in 76% of cases and only cutaneous in 24%. Cutaneous lesions were found in 66,66% of cases. Presenting features were cutaneous (46%), general (30%), rheumatoid, (16,6%), Lofgren syndrome (3 cases). The cutaneous lesions were specific in 94% of cases as small nodules (50%), placards (20%), great nodules (15%) and scars sarcoidosis (10%). Extra cutaneous involvement were pulmonary (73,33%), lymphadenopathy (66,66%), and rheumatoid (20%). Pulmonary tuberculosis was associated in 4 cases.
Our data confirmed rarity of sarcoidosis in Senegal opposite to the high reported frequency in other black population in developed country. Clinical features were polymorph and the systemic forms predominant. Tuberculosis may be rule out in order to avoid miss diagnosis.
尽管黑人中结节病的发病率很高，但塞内加尔很少有结节病病例报告。这项工作的目的是确定达喀尔结节病的流行病学、临床和评估特征。
我们进行了一项多中心回顾性试验，以描述1968年至2004年塞内加尔结节病病例的特征。
观察到20例（21名女性和9名男性）。平均年龄为40岁。20例患者首次就医前的病程长达一年。10名患者在结节病诊断前接受了抗结核治疗。结节病在76%的病例中是全身性疾病，仅24%为皮肤型。66.66%的病例发现有皮肤病变。表现特征为皮肤型（46%）、全身型（30%）、类风湿型（16.6%）、洛弗格伦综合征（3例）。94%的病例皮肤病变具有特异性，如小结节（50%）、斑块（20%）、大结节（15%）和结节病瘢痕（10%）。皮肤外受累部位为肺部（73.33%）、淋巴结病（66.66%）和类风湿型（20%）。4例合并肺结核。
我们的数据证实了塞内加尔结节病的罕见性，这与发达国家其他黑人人群中报道的高发病率相反。临床特征多样，以全身型为主。为避免漏诊，可能需要排除结核病。
