非动脉炎性前部缺血性视神经病变患者的球后血流动力学与颈动脉壁厚度
Retrobulbar haemodynamics and carotid wall thickness in patients with non-arteritic anterior ischaemic optic neuropathy.
作者信息
Sanjari M Soltan, Falavarjani K Ghasemi, Mehrabani M, Ghiasian L, Zamani B
机构信息
Eye Research Center, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
出版信息
Br J Ophthalmol. 2009 May;93(5):638-40. doi: 10.1136/bjo.2008.144832. Epub 2008 Dec 19.
AIM
To compare retrobulbar haemodynamics and ipsilateral carotid wall thickness of patients with unilateral non-arteritic anterior ischaemic optic neuropathy (NAION) with their contralateral side.
METHODS
Seventeen patients with unilateral NAION participated in this study. By means of Colour Doppler imaging, the blood-flow velocities of the ophthalmic artery were measured. Intima-media thickness (IMT) of common carotid and internal carotid arteries were measured using B-mode ultrasonography. Measurements of the affected side were compared with the non-involved side.
RESULTS
Flow velocities in the ophthalmic arteries on the side of the eyes with NAION were significantly decreased compared with those on the side of the unaffected eyes (p<0.001). In addition, in all patients, both common and internal carotid artery IMT were significantly greater on the side of the NAION compared with the contralateral side (p<0.001).
CONCLUSION
NAION may be associated with decreased retrobulbar flow velocities and increased carotid wall thickness.
目的
比较单侧非动脉炎性前部缺血性视神经病变（NAION）患者患侧与对侧的球后血流动力学及同侧颈动脉壁厚度。
方法
17例单侧NAION患者参与本研究。采用彩色多普勒成像测量眼动脉血流速度。使用B型超声测量颈总动脉和颈内动脉的内膜中层厚度（IMT）。将患侧测量值与未受累侧进行比较。
结果
与未受影响眼侧相比，NAION眼侧的眼动脉血流速度显著降低（p<0.001）。此外，在所有患者中，NAION侧的颈总动脉和颈内动脉IMT均显著大于对侧（p<0.001）。
结论
NAION可能与球后血流速度降低和颈动脉壁厚度增加有关。
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