Sanjari M Soltan, Falavarjani K Ghasemi, Mehrabani M, Ghiasian L, Zamani B
Eye Research Center, Rassoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
Br J Ophthalmol. 2009 May;93(5):638-40. doi: 10.1136/bjo.2008.144832. Epub 2008 Dec 19.
To compare retrobulbar haemodynamics and ipsilateral carotid wall thickness of patients with unilateral non-arteritic anterior ischaemic optic neuropathy (NAION) with their contralateral side.
Seventeen patients with unilateral NAION participated in this study. By means of Colour Doppler imaging, the blood-flow velocities of the ophthalmic artery were measured. Intima-media thickness (IMT) of common carotid and internal carotid arteries were measured using B-mode ultrasonography. Measurements of the affected side were compared with the non-involved side.
Flow velocities in the ophthalmic arteries on the side of the eyes with NAION were significantly decreased compared with those on the side of the unaffected eyes (p<0.001). In addition, in all patients, both common and internal carotid artery IMT were significantly greater on the side of the NAION compared with the contralateral side (p<0.001).
NAION may be associated with decreased retrobulbar flow velocities and increased carotid wall thickness.
比较单侧非动脉炎性前部缺血性视神经病变（NAION）患者患侧与对侧的球后血流动力学及同侧颈动脉壁厚度。
17例单侧NAION患者参与本研究。采用彩色多普勒成像测量眼动脉血流速度。使用B型超声测量颈总动脉和颈内动脉的内膜中层厚度（IMT）。将患侧测量值与未受累侧进行比较。
与未受影响眼侧相比，NAION眼侧的眼动脉血流速度显著降低（p<0.001）。此外，在所有患者中，NAION侧的颈总动脉和颈内动脉IMT均显著大于对侧（p<0.001）。
NAION可能与球后血流速度降低和颈动脉壁厚度增加有关。
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