Suppr超能文献

用于带状疱疹性眼病视力康复的I型波士顿人工角膜联合白内障摘除及人工晶状体植入术:“KPro三联手术”

Type I Boston keratoprosthesis with cataract extraction and intraocular lens placement for visual rehabilitation of herpes zoster ophthalmicus: the "KPro Triple".

作者信息

Todani A, Gupta P, Colby K

机构信息

Massachusetts Eye & Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA.

出版信息

Br J Ophthalmol. 2009 Jan;93(1):119. doi: 10.1136/bjo.2008.146415.

Abstract

INTRODUCTION

Management of corneal scarring following herpes zoster ophthalmicus (HZO) is challenging due to the dense corneal anesthesia that results from viral damage to the subepithelial nerve plexus. These patients have significant risk of graft failure following traditional corneal transplantation. We present a case of a 74-year-old white woman with counting fingers vision from HZO-associated corneal scarring and mature cataract where visual rehabilitation was accomplished with a Type I Boston keratoprosthesis (KPro) and concurrent extracapsular cataract extraction and posterior chamber intraocular lens placement (the "KPro Triple"). One month following surgery, the patient's uncorrected visual acuity improved to 20/25; this level of vision has been maintained for 7 months at present.

SURGICAL TECHNIQUE (SEE VIDEO): The keratoprosthesis is assembled by creating a sandwich composed of the KPro front plate, the donor cornea, and the KPro backplate that is secured with a locking ring. The host cornea is then trephined and posterior synechiae lysed to allow access to the mature cataract. The cataract is manually expressed and a posterior chamber intraocular lens implanted. The assembled keratoprosthesis is then sutured into position with 9.0 nylon. A bandage contact lens is placed.

COMMENT

In patients with severe neurotrophic keratopathy, traditional penetrating keratoplasty is fraught with problems, including poor epithelial healing and corneal ulceration. The Boston KPro can provide rapid visual rehabilitation, despite corneal anaesthesia in these patients, and is currently our treatment of choice as a primary procedure for HZO patients who need corneal transplantation.

摘要

引言

由于带状疱疹性眼炎(HZO)导致上皮下神经丛受到病毒损伤,进而引起严重的角膜麻醉,因此对HZO后角膜瘢痕的处理具有挑战性。这些患者在进行传统角膜移植后发生移植失败的风险很高。我们报告一例74岁白人女性患者,因HZO相关角膜瘢痕和成熟白内障而仅有数指视力,通过I型波士顿人工角膜(KPro)联合囊外白内障摘除及后房型人工晶状体植入术(“KPro三联手术”)实现了视觉康复。术后1个月,患者的未矫正视力提高到20/25;目前该视力水平已维持7个月。

手术技术(见视频):人工角膜由KPro前板、供体角膜和KPro后板组成三明治结构,并用锁定环固定。然后对宿主角膜进行环钻,松解后粘连,以便处理成熟白内障。手动挤出白内障并植入后房型人工晶状体。然后用9.0尼龙线将组装好的人工角膜缝合到位。放置绷带式隐形眼镜。

评论

对于严重神经营养性角膜病变患者,传统穿透性角膜移植术存在诸多问题,包括上皮愈合不良和角膜溃疡。尽管这些患者存在角膜麻醉,但波士顿KPro可实现快速视觉康复,目前是我们对需要角膜移植的HZO患者作为主要手术的首选治疗方法。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验