Kofinas A D, Simon N V, Sagel H, Lyttle E, Smith N, King K
Department of Obstetrics and Gynecology, York Hospital, PA 17405.
Am J Obstet Gynecol. 1991 Sep;165(3):630-1. doi: 10.1016/0002-9378(91)90298-6.
Transplacentally administered digoxin is the drug of choice for the treatment of fetal supraventricular tachycardia. We describe a case of fetal supraventricular tachycardia associated with fetal hydrops that did not respond to digoxin treatment because of a lack of transplacental passage. In contrast, flecainide acetate crossed the placenta and cured the fetus. The clinical implications of this new treatment are discussed.
经胎盘给予地高辛是治疗胎儿室上性心动过速的首选药物。我们描述了一例与胎儿水肿相关的胎儿室上性心动过速病例，该病例由于缺乏经胎盘转运而对地高辛治疗无反应。相比之下，醋酸氟卡尼可穿过胎盘并治愈了胎儿。本文讨论了这种新治疗方法的临床意义。
