Russell Judith, Kazantzis Nikolaos
Child andAdolescent Mental Health Services, Counties Manukau District Health Board, Manukau, Auckland.
N Z Med J. 2008 Nov 7;121(1286):14-20.
The aim of this study was to determine whether patient beliefs about the necessity and concerns about medication were associated with adherence among those presenting with depression in primary care.
At the end of a routine consultation with their general medical practitioner, patients completed questionnaires including measures of beliefs about medication, self reported adherence, depression severity, and demographic information.
A significant relationship between beliefs in the necessity of antidepressants and adherence was not found. However, patient concerns with medications were positively associated with non-adherence. Where beliefs about the necessity outweighed concerns about taking the medication, significantly greater adherence was observed. Fewer depressive symptoms were also associated with greater adherence.
This study extended prior research on the role of patient beliefs in medication adherence for chronic physical health problems by showing the belief-adherence relationship in a depressed patient sample. A balance between beliefs about the costs and benefits of medication are likely to be important in understanding adherence with other medications.
本研究旨在确定在初级保健中就诊的抑郁症患者对药物必要性的信念以及对药物的担忧是否与依从性相关。
在与全科医生进行常规会诊结束时，患者完成问卷调查，包括对药物信念的测量、自我报告的依从性、抑郁严重程度和人口统计学信息。
未发现对抗抑郁药必要性的信念与依从性之间存在显著关系。然而，患者对药物的担忧与不依从呈正相关。当对必要性的信念超过对服药的担忧时，观察到依从性显著更高。较少的抑郁症状也与更高的依从性相关。
本研究通过在抑郁症患者样本中展示信念与依从性的关系，扩展了先前关于患者信念在慢性身体健康问题药物依从性中作用的研究。药物成本效益信念之间的平衡可能对理解其他药物的依从性很重要。
