由马达蛋白驱动的组装胶囊运输。

Assembled capsules transportation driven by motor proteins.

作者信息

Song Weixing, He Qiang, Cui Yue, Möhwald Helmuth, Diez Stefan, Li Junbai

机构信息

Beijing National Laboratory for Molecular Sciences, International Joint Lab, Institute of Chemistry, Chinese Academy of Sciences, Zhong Guan Cun, Bei Yi Jie No. 2, 100190 Beijing, China.

出版信息

Biochem Biophys Res Commun. 2009 Feb 6;379(2):175-8. doi: 10.1016/j.bbrc.2008.11.136. Epub 2008 Dec 25.

DOI:10.1016/j.bbrc.2008.11.136

PMID:19100716

Abstract

An active biomimetic system by integrating kinesin motor, microtubule, and man-made biomimetic microcapsule has been constructed. Biomimetic microcapsules were fabricated by using the layer-by-layer technique and could serve as cargos in this active biomimetic system. Both of the hollow and filled capsules as cargos can be transported by kinesin motors along microtubules. It may help to create kinesin-powered complex hybrid micro- and nanodevices.

摘要

通过整合驱动蛋白马达、微管和人造仿生微胶囊构建了一个活性仿生系统。仿生微胶囊采用层层技术制备，可作为该活性仿生系统中的货物。作为货物的空心胶囊和填充胶囊都可以由驱动蛋白马达沿着微管运输。这可能有助于制造由驱动蛋白驱动的复杂混合微纳器件。