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Taurine release from brain slices in thioacetamide-induced hepatic encephalopathy in rats.

作者信息

Wysmyk U, Oja S S, Saransaari P

机构信息

Tampere Brain Research Center, Department of Biomedical Sciences, University of Tampere, Tampere, Finland.

出版信息

Mol Chem Neuropathol. 1991 Feb;14(1):25-34. doi: 10.1007/BF03160995.

DOI:10.1007/BF03160995
PMID:1910355
Abstract

The possible involvement of taurine in the pathogenesis of hepatic encephalopathy was studied in rats injected with thioacetamide. Spontaneous release of exogenous labeled taurine was not affected in any brain area studied, but the potassium-stimulated release was enhanced in the striatum in thioacetamide-treated rats. High concentrations of ammonium ions also evoked greater release of taurine from striatal slices in rats with thioacetamide-induced hepatic encephalopathy.

摘要

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