• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

下肢严重创伤后的并发症。

Complications following limb-threatening lower extremity trauma.

作者信息

Harris Anthony M, Althausen Peter L, Kellam James, Bosse Michael J, Castillo Renan

机构信息

Department of Orthopaedics Trauma Division, Shands Jacksonville, Jacksonville, FL 32209, USA.

出版信息

J Orthop Trauma. 2009 Jan;23(1):1-6. doi: 10.1097/BOT.0b013e31818e43dd.

DOI:10.1097/BOT.0b013e31818e43dd
PMID:19104297
Abstract

OBJECTIVE

Our objective is to report the nature and incidence of major complications after severe lower extremity trauma.

DESIGN

Multicenter, prospective, observational study.

SETTING

Eight level-1 trauma centers.

PATIENTS/PARTICIPANTS: Five hundred forty-five patients were followed for 2 years.

INTERVENTION

Amputation or reconstruction.

MAIN OUTCOME MEASUREMENTS

The type and number of complications associated with these injuries were recorded at baseline, 3-, 6-, 12-, and 24-month intervals.

RESULTS

One hundred forty-nine underwent amputation during the initial hospitalization. The revision amputation rate was 5.4%. Among the amputation group, a complication was noted most frequently at 3 months (24.8%), and the most commonly seen complication was wound infection (34.2%). Wound complications including dehiscence (13.4%) were seen more commonly in the amputation group. Three hundred seventy-one limb reconstructions were performed with 25 patients (3.9%) requiring late amputation. The most frequently reported complication was at 6 months for the salvage group (37.7%), and the most commonly seen complication was wound infection (23.2%). Not surprisingly, osteomyelitis (8.6%) and nonunions (31%) were seen more commonly in the salvage group. Complications of wound infection, osteomyelitis, nonunion, malunion, and prominent hardware resulted in rehospitalization in at least one-third of patients. However, patients who underwent reconstruction were more likely to be hospitalized for these complications.

CONCLUSIONS

Patients with severe lower extremity injuries can expect a significant number of complications, most notably wound infection, nonunion, wound necrosis, and osteomyelitis. A large portion of these will require additional inpatient or operative treatment. Patients electing for reconstruction can expect a higher risk of complications.

摘要

目的

我们的目的是报告严重下肢创伤后主要并发症的性质和发生率。

设计

多中心、前瞻性、观察性研究。

地点

八个一级创伤中心。

患者/参与者:545例患者随访2年。

干预措施

截肢或重建。

主要观察指标

在基线、3个月、6个月、12个月和24个月时记录与这些损伤相关的并发症类型和数量。

结果

149例在初次住院期间接受了截肢。再次截肢率为5.4%。在截肢组中,并发症最常出现在3个月时(24.8%),最常见的并发症是伤口感染(34.2%)。伤口并发症包括裂开(13.4%)在截肢组中更常见。进行了371例肢体重建,25例患者(3.9%)需要后期截肢。挽救组最常报告的并发症出现在6个月时(37.7%),最常见的并发症是伤口感染(23.2%)。不出所料,骨髓炎(8.6%)和骨不连(31%)在挽救组中更常见。伤口感染、骨髓炎、骨不连、畸形愈合和内固定物突出等并发症导致至少三分之一的患者再次住院。然而,接受重建的患者因这些并发症住院的可能性更大。

结论

严重下肢损伤患者可能会出现大量并发症,最显著的是伤口感染、骨不连、伤口坏死和骨髓炎。其中很大一部分需要额外的住院或手术治疗。选择重建的患者并发症风险更高。

相似文献

1
Complications following limb-threatening lower extremity trauma.下肢严重创伤后的并发症。
J Orthop Trauma. 2009 Jan;23(1):1-6. doi: 10.1097/BOT.0b013e31818e43dd.
2
Gustilo IIIC fractures in the lower limb: our 15-year experience.下肢 Gustilo IIIC 型骨折:我们的 15 年经验
J Bone Joint Surg Br. 2012 May;94(5):698-703. doi: 10.1302/0301-620X.94B5.27948.
3
Distal interphalangeal joint arthrodesis: an analysis of complications.
J Hand Surg Am. 1992 Nov;17(6):1139-45. doi: 10.1016/s0363-5023(09)91081-4.
4
An analysis of outcomes of reconstruction or amputation after leg-threatening injuries.对威胁肢体损伤后重建或截肢结局的分析。
N Engl J Med. 2002 Dec 12;347(24):1924-31. doi: 10.1056/NEJMoa012604.
5
Late amputation may not reduce complications or improve mental health in combat-related, lower extremity limb salvage patients.对于与战斗相关的下肢肢体挽救患者,晚期截肢可能无法减少并发症或改善心理健康状况。
Injury. 2015 Aug;46(8):1527-32. doi: 10.1016/j.injury.2015.05.015. Epub 2015 May 14.
6
Limb salvage after vascular reconstruction followed by tissue transfer during the Global War on Terror.在反恐全球战争期间,血管重建后行组织移植进行肢体挽救。
J Vasc Surg. 2015 Mar;61(3):734-40. doi: 10.1016/j.jvs.2014.10.039. Epub 2014 Dec 9.
7
Limb salvage of lower-extremity wounds using free gracilis muscle reconstruction.采用游离股薄肌重建术对下肢伤口进行保肢治疗。
Plast Reconstr Surg. 2000 Dec;106(7):1507-13. doi: 10.1097/00006534-200012000-00010.
8
Short-term wound complications after application of flaps for coverage of traumatic soft-tissue defects about the tibia. The Lower Extremity Assessment Project (LEAP) Study Group.应用皮瓣覆盖胫骨周围创伤性软组织缺损后的短期伤口并发症。下肢评估项目(LEAP)研究小组。
J Bone Joint Surg Am. 2000 Dec;82(12):1681-91.
9
Infectious complications and soft tissue injury contribute to late amputation after severe lower extremity trauma.感染性并发症和软组织损伤是导致严重下肢创伤后晚期截肢的原因。
J Trauma. 2011 Jul;71(1 Suppl):S47-51. doi: 10.1097/TA.0b013e318221181d.
10
Fasciocutaneous free flaps are more reliable than muscle free flaps in lower limb trauma reconstruction: experience in a single trauma center.筋膜皮瓣游离移植比肌肉游离皮瓣在下肢创伤重建中更可靠:单中心创伤中心经验。
J Reconstr Microsurg. 2012 Jun;28(5):333-40. doi: 10.1055/s-0032-1313764. Epub 2012 May 15.

引用本文的文献

1
Use of micro-grafts in a chronic infected open wound after limb amputation in a cat.微移植在猫肢体截肢术后慢性感染开放性伤口中的应用。
Vet Med (Praha). 2021 Oct 31;66(10):448-455. doi: 10.17221/197/2020-VETMED. eCollection 2021 Oct.
2
Acute Complications of United States Service Members with Combat-Related Lower Extremity Limb Salvage.美国与战斗相关的下肢肢体挽救服务成员的急性并发症
J Clin Med. 2025 Jun 3;14(11):3923. doi: 10.3390/jcm14113923.
3
Characterization of Secondary Health Conditions Among United States Service Members with Combat-Related Lower Extremity Limb Salvage.
美国与战斗相关的下肢肢体挽救服务成员的继发性健康状况特征
J Clin Med. 2025 May 15;14(10):3472. doi: 10.3390/jcm14103472.
4
Healthcare Utilization Among United States Service Members with Combat-Related Lower Extremity Limb Salvage.美国下肢与战斗相关肢体挽救的服役人员的医疗保健利用情况。
Healthcare (Basel). 2025 May 16;13(10):1164. doi: 10.3390/healthcare13101164.
5
Impact of delayed amputation on clinical outcomes compared to that of early amputation in patients with blunt polytrauma.钝性多发伤患者中,与早期截肢相比,延迟截肢对临床结局的影响。
Sci Rep. 2025 Mar 10;15(1):8184. doi: 10.1038/s41598-025-93322-9.
6
A Cost-Effectiveness Analysis of Intramedullary Nailing Versus External Fixation for Open Tibial Fractures in Tanzania.坦桑尼亚开放性胫骨骨折髓内钉固定与外固定的成本效益分析
JB JS Open Access. 2025 Feb 21;10(1). doi: 10.2106/JBJS.OA.24.00006. eCollection 2025 Jan-Mar.
7
Complex Limb Injuries: Limb Salvage Versus Amputation-A Mini Review and Meta-Analysis.复杂肢体损伤:保肢与截肢——一项小型综述与荟萃分析
Adv Orthop. 2025 Jan 30;2025:2884802. doi: 10.1155/aort/2884802. eCollection 2025.
8
Does the CDC Surgical Wound Classification adequately predict postoperative infection in lower extremity fracture surgery?美国疾病控制与预防中心(CDC)的手术伤口分类能否充分预测下肢骨折手术的术后感染?
OTA Int. 2025 Jan 17;8(1):e357. doi: 10.1097/OI9.0000000000000357. eCollection 2025 Mar.
9
Clinical Assessment and Factors Influencing Treatment Strategy and Outcomes in Complex Limb Injuries.复杂肢体损伤的临床评估及影响治疗策略和预后的因素
Cureus. 2024 Nov 9;16(11):e73347. doi: 10.7759/cureus.73347. eCollection 2024 Nov.
10
Staged Limb Reconstruction Using Ilizarov Fixator in an Infected Tibia Nonunion: A Case Report.使用伊利扎罗夫固定器分期进行肢体重建治疗感染性胫骨骨不连:一例报告
Cureus. 2024 Aug 18;16(8):e67112. doi: 10.7759/cureus.67112. eCollection 2024 Aug.