Enomoto Katsuhisa, Sakurai Kenichi, Amano Sadao, Shiono Motomi
Division of General, Breast and Endocrine and Respiratory Surgery, Dept. of Surgery, Nihon University School of Medicine.
Gan To Kagaku Ryoho. 2008 Nov;35(12):2225-7.
The case reported here was a 40-year-old woman. She came to our hospital because we palpated on her left breast to locate a tumor. The clinical history showed a breast flabellate resection and lymphadenectomy for carcinoma of the left breast in 2000. The tumor was scirrhous type, and the histopathology diagnosis showed it to be T2N0M0 stage IIA, and the hormone receptor was ER (-), PgR (-). As an outpatient, we performed radiotherapy. In 2006, we confirmed a tumor on the right side under the left breast wounded area. We left the tumor without a treatment. However, the tumor had a tendency to grow in size and was Class V in aspiration biopsy cytology, and was diagnosed of sarcoma by needle biopsy. The patient was hospitalized in order to have a surgery. We performed a pectoralis muscle merger mastectomy and a chest wall restoration by latissimus dorsi muscle dermal flap in March 2007. Histopathology diagnosis revealed it to be malignant fibrous histiocytoma (MFH). At present, the patient has been treated as an outpatient. There has been neither recurrence nor a metastasis with the patient. The patient has recently been treated with radiotherapy for the remaining breast after a breast preservation surgery. We reported our case with a possibility of MFH occurrence in addition to some article considerations.
此处报告的病例是一名40岁女性。她因我们在其左乳触诊发现肿瘤而来我院就诊。临床病史显示其于2000年因左乳癌接受了乳房扇形切除术和淋巴结清扫术。肿瘤为硬癌类型，组织病理学诊断显示为T2N0M0 ⅡA期，激素受体为ER（-），PgR（-）。作为门诊患者，我们对其进行了放疗。2006年，我们在左乳伤口下方右侧确认有一个肿瘤。我们未对该肿瘤进行治疗。然而，该肿瘤有增大趋势，针吸活检细胞学检查为V级，经穿刺活检诊断为肉瘤。患者住院准备接受手术。2007年3月，我们为其实施了胸大肌合并乳房切除术，并采用背阔肌肌皮瓣进行胸壁修复。组织病理学诊断显示为恶性纤维组织细胞瘤（MFH）。目前，该患者作为门诊患者接受治疗。患者既无复发也无转移。该患者近期在保乳手术后对剩余乳房进行了放疗。我们报告了本病例，并结合一些文献考量探讨了发生MFH的可能性。
