Thomas F, Berthout A, Malthieu D, Turut P, Milazzo S
Service d'ophtalmologie, CHU d'Amien, Centre Saint-Victor, Amiens.
J Fr Ophtalmol. 2008 Dec;31(10):e21. doi: 10.1016/s0181-5512(08)74750-8.
Chronic central serous chorioretinopathy (CCSC) with recurrent and prolonged exudative retinal detachment may cause multiple degenerative manifestations with poor visual acuity. By acting on choroidal hyperpermeability, photodynamic therapy seems to be a useful treatment for symptomatic CCSC. We present the case of a 60-year-old patient presenting with symptomatic CCSC complicated with serous retinal detachment lasting more than 1 year. Visual acuity on the left eye was 1/20. Photodynamic therapy with indocyanine green angiography guidance was provided. Subretinal fluid was rapidly resolved and visual acuity improved to 7/10. Photodynamic therapy influences choroidal hyperpermeability and thus resolves serous retinal detachment in CCSC. Visual acuity improvement particularly depends on preexisting macular atrophy.
慢性中心性浆液性脉络膜视网膜病变(CCSC)伴复发性和持续性渗出性视网膜脱离可能导致多种退行性表现,视力不佳。通过作用于脉络膜高通透性,光动力疗法似乎是有症状CCSC的一种有效治疗方法。我们报告一例60岁有症状CCSC合并浆液性视网膜脱离持续超过1年的患者。左眼视力为1/20。给予吲哚菁绿血管造影引导下的光动力疗法。视网膜下液迅速消退,视力提高到7/10。光动力疗法影响脉络膜高通透性,从而解决CCSC中的浆液性视网膜脱离。视力改善尤其取决于既往存在的黄斑萎缩。