Zhao Jing, Han Bing, Shen Ti, Zhao Yongqiang, Wang Tao, Liu Yuehua, Fang Kai, Zhong Dingrong, Ling Qing
Department of Hematology, Peking Union Medical College Hospital, 100730, Beijing, China.
Department of Dermatology, Peking Union Medical College Hospital, 100730, Beijing, China.
Int J Hematol. 2009 Jan;89(1):113-117. doi: 10.1007/s12185-008-0201-5. Epub 2008 Dec 26.
We report a case of a 58-year-old man who presented with a rapidly growing proliferative lesion on the left lower limb, clinically resembling a soft tissue sarcoma 3 years after renal allograft. There was no evidence of systemic involvement on bone marrow needle aspiration and computed tomography (CT) scans of the chest and abdomen. The lesion turned out to be primary cutaneous diffuse large B-cell lymphoma, leg type (PCLBCL LT), as defined in the recent World Health Organization-European Organization for Research and Treatment of Cancer (WHO-EORTC) classification of cutaneous lymphomas by skin biopsy. Immunosuppression reduction, chemotherapy with CHOP regimen and local radiotherapy induced complete remission of the tumor.
我们报告一例58岁男性，肾移植3年后左下肢出现快速生长的增殖性病变，临床症状类似软组织肉瘤。骨髓穿刺活检及胸部和腹部计算机断层扫描（CT）均未发现全身受累迹象。经皮肤活检，该病变被确诊为原发性皮肤弥漫性大B细胞淋巴瘤，腿部型（PCLBCL LT），这是最近世界卫生组织-欧洲癌症研究与治疗组织（WHO-EORTC）皮肤淋巴瘤分类中定义的类型。减少免疫抑制、采用CHOP方案化疗及局部放疗使肿瘤完全缓解。
