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乳腺积乳囊肿与泌乳素瘤——一种致病关联?

Galactocele and prolactinoma--a pathogenic association?

作者信息

Poiana Catalina, Chirita Corina, Carsote Mara, Hortopan Dan, Goldstein Andrei

机构信息

Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.

出版信息

Maturitas. 2009 Jan 20;62(1):98-102. doi: 10.1016/j.maturitas.2008.10.015. Epub 2008 Dec 24.

DOI:10.1016/j.maturitas.2008.10.015
PMID:19110385
Abstract

A galactocele is a rare form of cystic, benign lesion of the breast, appearing when a mammary duct becomes obstructed and over filled with milk. It is usually found in postpartum women, either lactating or not. There are only a few cases reported that are not immediately linked to the lactation, as seen in postmenopausal women or in men. Furthermore, the relationship to overproduction of prolactine, a growth factor for the breast epithelium is not very well defined at this moment. We present such an unusual case of a 37-year-old female patient who has no history of birth or abortion. She was diagnosed with both microprolactinoma and galactocele whose dimensions seemed to be related to the evolution of the pituitary tumor and serum prolactine. Because no other etiology could be found in the young patient for the mammary galactocele, the prolactine excess is the most probable cause. Even considering the rarity of the association it is important to point the hormonal role in changing the anatomy of the breast.

摘要

乳腺积乳囊肿是一种罕见的乳腺囊性良性病变,当乳腺导管阻塞并充满乳汁时出现。它通常见于产后女性,无论是否处于哺乳期。仅有少数病例报道与哺乳无直接关联,如绝经后女性或男性。此外,与催乳素(一种乳腺上皮生长因子)分泌过多的关系目前尚未完全明确。我们在此呈现一例不同寻常的病例,患者为37岁女性,无生育或流产史。她被诊断患有微泌乳素瘤和乳腺积乳囊肿,其大小似乎与垂体瘤及血清催乳素的变化有关。由于在这位年轻患者中未发现其他导致乳腺积乳囊肿的病因,催乳素分泌过多很可能是病因。即便考虑到这种关联较为罕见,但指出激素在改变乳腺解剖结构中的作用仍很重要。

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Galactocele and prolactinoma--a pathogenic association?乳腺积乳囊肿与泌乳素瘤——一种致病关联?
Maturitas. 2009 Jan 20;62(1):98-102. doi: 10.1016/j.maturitas.2008.10.015. Epub 2008 Dec 24.
2
[A rare case of giant galactocele associated with prolactinoma].[1例罕见的巨大乳腺囊肿合并泌乳素瘤病例]
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[A rare case of giant galactocele associated with prolactinoma].[1例罕见的巨大乳腺囊肿合并泌乳素瘤病例]
Pan Afr Med J. 2017 Jun 8;27:97. doi: 10.11604/pamj.2017.27.97.12484. eCollection 2017.
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