Li Chaoyang, Ford Earl S, Zhao Guixiang, Ahluwalia Indu B, Pearson William S, Mokdad Ali H
Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30341, USA.
Diabetes Res Clin Pract. 2009 Feb;83(2):268-79. doi: 10.1016/j.diabres.2008.11.006. Epub 2008 Dec 25.
Many people with depression may be undiagnosed and thus untreated. We sought to assess the prevalence and correlates of undiagnosed depression among adults with diabetes.
Data of U.S. adults from the Behavioral Risk Factor Surveillance System in 2006 were analyzed. Cox proportional hazard regression analysis was used to estimate prevalence ratios (PRs) and 95% confidence intervals (CIs) of correlates for undiagnosed depression.
The unadjusted and age-adjusted prevalences of undiagnosed depression were 8.7% and 9.2%. About 45% of diabetes patients with depression were undiagnosed. After adjustments for all correlates, female gender (PR, 1.4; 95% CI: 1.1-1.8), poor or fair health (PR, 2.8; 95% CI: 2.1-3.6), lack of social and emotional support (PR, 2.5; 95% CI: 1.8-3.3), life dissatisfaction (PR, 3.5; 95% CI: 2.2-5.5), use of special equipment (PR, 1.4; 95% CI: 1.1-1.8), no leisure-time physical activity (PR, 1.5; 95% CI: 1.2-1.9), and comorbid cardiovascular disease (PR, 1.5; 95% CI: 1.2-1.9) were associated with undiagnosed depression.
Undiagnosed depression among people with diabetes was common. Because depression is associated with increased risk of diabetes-related complications, early detection of depression is needed in clinical settings.
许多抑郁症患者可能未被诊断出来,因此未得到治疗。我们试图评估糖尿病成年患者中未被诊断出的抑郁症的患病率及其相关因素。
分析了2006年美国行为危险因素监测系统中成年患者的数据。采用Cox比例风险回归分析来估计未被诊断出的抑郁症相关因素的患病率比值(PRs)和95%置信区间(CIs)。
未被诊断出的抑郁症的未调整患病率和年龄调整患病率分别为8.7%和9.2%。约45%的抑郁症糖尿病患者未被诊断出来。在对所有相关因素进行调整后,女性(PR,1.4;95%CI:1.1 - 1.8)、健康状况差或一般(PR,2.8;95%CI:2.1 - 3.6)、缺乏社会和情感支持(PR,2.5;95%CI:1.8 - 3.3)、生活不满意(PR,3.5;95%CI:2.2 - 5.5)、使用特殊设备(PR,1.4;95%CI:1.1 - 1.8)、无休闲时间体育活动(PR,1.5;95%CI:1.2 - 1.9)以及合并心血管疾病(PR,1.5;95%CI:1.2 - 1.9)与未被诊断出的抑郁症相关。
糖尿病患者中未被诊断出的抑郁症很常见。由于抑郁症与糖尿病相关并发症风险增加有关,因此在临床环境中需要早期发现抑郁症。