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澳大利亚年轻女性的妊娠丢失:来自澳大利亚女性健康纵向研究的结果。

Pregnancy losses in young Australian women: findings from the Australian Longitudinal Study on Women's Health.

作者信息

Herbert Danielle, Lucke Jayne, Dobson Annette

机构信息

The University of Queensland, School of Population Health, Brisbane, Australia.

出版信息

Womens Health Issues. 2009 Jan-Feb;19(1):21-9. doi: 10.1016/j.whi.2008.08.007.

Abstract

INTRODUCTION

Little research has examined recognized pregnancy losses in a general population. Data from an Australian cohort study provide an opportunity to quantify this aspect of fecundity at a population level.

METHOD

Participants in the Australian Longitudinal Study on Women's Health who were aged 28-33 years in 2006 (n = 9,145) completed up to 4 mailed surveys over 10 years. Participants were categorized according to the recognized outcome of their pregnancies, including live birth, miscarriage/stillbirth, termination/ectopic, or no pregnancy.

RESULTS

At age 18-23, more women reported terminations (7%) than miscarriages (4%). By 28-33 years, the cumulative frequency of miscarriage (15%) was as common as termination (16%). For women aged 28-33 years who had ever been pregnant (n = 5,343), pregnancy outcomes were as follows: birth only (50%); loss only (18%); and birth and loss (32%), of which half (16%) were birth and miscarriage. A comparison between first miscarriage and first birth (no miscarriage) showed that most first miscarriages occurred in women aged 18-23 years who also reported a first birth at the same survey (15%). Half (51%) of all first births and first miscarriages in women aged 18-19 ended in miscarriage. Early childbearers (<28 years) often had miscarriages around the same time period as their first live birth, suggesting proactive family formation. Delayed childbearers (32-33 years) had more first births than first miscarriages.

CONCLUSION

Recognized pregnancy losses are an important measure of fecundity in the general population because they indicate successful conception and maintenance of pregnancy to varying reproductive endpoints.

摘要

引言

很少有研究在普通人群中调查已确认的妊娠丢失情况。澳大利亚一项队列研究的数据提供了一个在人群层面量化生育力这一方面的机会。

方法

参加澳大利亚女性健康纵向研究的参与者在2006年年龄为28 - 33岁(n = 9145),在10年期间完成了多达4次邮寄调查问卷。参与者根据其妊娠的已确认结果进行分类,包括活产、流产/死产、终止妊娠/异位妊娠或未妊娠。

结果

在18 - 23岁时,报告终止妊娠的女性(7%)多于流产的女性(4%)。到28 - 33岁时,流产的累积发生率(15%)与终止妊娠的累积发生率(16%)相当。对于28 - 33岁曾经怀孕的女性(n = 5343),妊娠结局如下:仅生育(50%);仅妊娠丢失(18%);生育和妊娠丢失(32%),其中一半(16%)是生育和流产。首次流产与首次生育(无流产)的比较表明,大多数首次流产发生在18 - 23岁且在同一次调查中也报告首次生育的女性中(15%)。18 - 19岁女性的所有首次生育和首次流产中有一半(51%)以流产告终。早育女性(<28岁)的流产时间通常与其首次活产时间相近,表明她们积极组建家庭。晚育女性(32 - 33岁)的首次生育多于首次流产。

结论

已确认的妊娠丢失是普通人群生育力的一项重要指标,因为它们表明了不同生殖终点的成功受孕和妊娠维持情况。

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