Leung F, Terzibachian J-J, Ramanah R, Govyadovskiy A, Aouar Z, Lassabe C, Riethmuller D
Service de gynécologie-obstétrique, CHU Saint-Jacques, Besançon, France.
J Gynecol Obstet Biol Reprod (Paris). 2009 Feb;38(1):72-6. doi: 10.1016/j.jgyn.2008.11.003. Epub 2008 Dec 27.
Rhabdomyosarcoma (RMS) of the uterine corpus is rare in adult females. This tumor can be encountered in two distinct histopathological contexts: usually as a component of a malignant mixed mullerian tumor and exceptionally as a pure heterologous sarcoma. We report two cases of pure RMS of the uterine corpus occurring in postmenopausal women. The two patients suffered from vaginal bleeding and preoperative diagnosis was achieved in both cases. Both patients benefited from exploratory laparotomy, total hysterectomy and bilateral salpingo-oophorectomy. Both of them were free from the disease 15 months and 1 year respectively, after initial surgery. These two observations are worthy of publication because pure RMS of the uterine corpus is exceptional in postmenopausal women.
子宫体横纹肌肉瘤(RMS)在成年女性中较为罕见。这种肿瘤可出现在两种不同的组织病理学背景下:通常作为恶性混合苗勒管肿瘤的一个组成部分,极少数情况下作为单纯的异源性肉瘤。我们报告两例发生在绝经后女性的子宫体纯RMS病例。两名患者均出现阴道出血,且两例均获得了术前诊断。两名患者均接受了剖腹探查术、全子宫切除术及双侧输卵管卵巢切除术。初次手术后,她们分别在15个月和1年后无病生存。这两例报道值得发表,因为子宫体纯RMS在绝经后女性中极为罕见。