Gong Xiaojing, Li Jingyuan, Zhang He, Wan Rongzheng, Lu Hangjun, Wang Shen, Fang Haiping
Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China.
Phys Rev Lett. 2008 Dec 19;101(25):257801. doi: 10.1103/PhysRevLett.101.257801. Epub 2008 Dec 15.
We used molecular dynamics simulation to study the effect of the external structure on water permeation across a single-walled nanochannel. In contrast with the macroscopic scenario, the outside structure greatly affects the water transport across the nanochannel. Remarkably, the ratio of maximal to minimal flux reached a value of about two for different outside structures. These findings are expected to be helpful in design of high-flux nanochannels and provide an insight into the contribution of the lipid membrane to water permeation across biological water channels.
我们使用分子动力学模拟来研究外部结构对单壁纳米通道水渗透的影响。与宏观情况不同，外部结构对纳米通道的水传输有很大影响。值得注意的是，对于不同的外部结构，最大通量与最小通量之比达到了约为2的值。这些发现有望有助于高通量纳米通道的设计，并深入了解脂质膜对生物水通道水渗透的贡献。
