Menzies Nick, Abang Betty, Wanyenze Rhoda, Nuwaha Fred, Mugisha Balaam, Coutinho Alex, Bunnell Rebecca, Mermin Jonathan, Blandford John M
US Centers for Disease Control and Prevention, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Atlanta, Georgia, USA.
AIDS. 2009 Jan 28;23(3):395-401. doi: 10.1097/QAD.0b013e328321e40b.
HIV counseling and testing (HCT) is a key intervention for HIV/AIDS control, and new strategies have been developed for expanding coverage in developing countries. We compared costs and outcomes of four HCT strategies in Uganda.
A retrospective cohort of 84 323 individuals received HCT at one of four Ugandan HCT programs between June 2003 and September 2005. HCT strategies assessed were stand-alone HCT; hospital-based HCT; household-member HCT; and door-to-door HCT.
We collected data on client volume, demographics, prior testing and HIV diagnosis from project monitoring systems, and cost data from project accounts and personnel interviews. Strategies were compared in terms of costs and effectiveness at reaching key population groups.
Household-member and door-to-door HCT strategies reached the largest proportion of previously untested individuals (>90% of all clients). Hospital-based HCT diagnosed the greatest proportion of HIV-infected individuals (27% prevalence), followed by stand-alone HCT (19%). Household-member HCT identified the highest percentage of discordant couples; however, this was a small fraction of total clients (<4%). Costs per client (2007 USD) were $19.26 for stand-alone HCT, $11.68 for hospital-based HCT, $13.85 for household-member HCT, and $8.29 for door-to-door-HCT.
All testing strategies had relatively low per client costs. Hospital-based HCT most readily identified HIV-infected individuals eligible for treatment, whereas home-based strategies more efficiently reached populations with low rates of prior testing and HIV-infected people with higher CD4 cell counts. Multiple HCT strategies with different costs and efficiencies can be used to meet the UNAIDS/WHO call for universal HCT access by 2010.
艾滋病毒咨询与检测(HCT)是控制艾滋病毒/艾滋病的一项关键干预措施,并且已制定了新战略以扩大在发展中国家的覆盖范围。我们比较了乌干达四种HCT战略的成本和结果。
2003年6月至2005年9月期间,一个由84323人组成的回顾性队列在乌干达四个HCT项目之一接受了HCT。评估的HCT战略包括独立HCT;基于医院的HCT;家庭成员HCT;以及挨家挨户HCT。
我们从项目监测系统收集了关于服务对象数量、人口统计学特征、既往检测情况和艾滋病毒诊断的数据,并从项目账目和人员访谈中收集了成本数据。对各战略在接触关键人群方面的成本和效果进行了比较。
家庭成员HCT和挨家挨户HCT战略覆盖了此前未接受检测的个人中的最大比例(占所有服务对象的90%以上)。基于医院的HCT诊断出的艾滋病毒感染者比例最高(患病率为27%),其次是独立HCT(19%)。家庭成员HCT识别出的不一致伴侣比例最高;然而,这在全部服务对象中所占比例很小(<4%)。每位服务对象的成本(2007年美元),独立HCT为19.26美元,基于医院的HCT为11.68美元,家庭成员HCT为13.85美元,挨家挨户HCT为8.29美元。
所有检测战略的每位服务对象成本相对较低。基于医院的HCT最容易识别出符合治疗条件的艾滋病毒感染者,而基于家庭的战略能更有效地接触到既往检测率低的人群以及CD4细胞计数较高的艾滋病毒感染者。可以采用具有不同成本和效率的多种HCT战略,以满足联合国艾滋病规划署/世界卫生组织关于到2010年普及HCT的要求。