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对希望保留生育功能的子宫内膜癌患者进行保守治疗:如何告知?

Conservative management of a patient with endometrial carcinoma desiring fertility: how to inform?

作者信息

Topuz S, Kalelioğlu I, Iyibozkurt C, Ergun B

机构信息

Department of Obstetrics and Gynecology, Istanbul University, School of Medicine, Turkey.

出版信息

Eur J Gynaecol Oncol. 2008;29(6):661-3.

PMID:19115702
Abstract

Conservative management of patients with endometrial cancer who desire fertility is becoming widespread in certain circumstances. A 36-year-old women desiring fertility with early-stage endometroid type adenocarcinoma of the endometrium was treated with 160 mg/d megestrol acetate for six months. After confirmation of a normal endometrial biopsy she became pregnant spontaneously. Following an uneventful pregnancy a healthy baby at term was delivered by cesarean section. Definitive surgery was performed. The risks and benefits of this thereupeutic approach are discussed and informing style of the patients emphasized.

摘要

在某些情况下,对希望保留生育能力的子宫内膜癌患者进行保守治疗正变得越来越普遍。一名36岁希望保留生育能力的早期子宫内膜样腺癌患者接受了每天160毫克醋酸甲地孕酮治疗六个月。在子宫内膜活检确认正常后,她自然受孕。经过顺利的孕期,足月时通过剖宫产分娩出一个健康的婴儿。随后进行了根治性手术。讨论了这种治疗方法的风险和益处,并强调了告知患者的方式。

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引用本文的文献

1
Challenging Regimen for Long-Term Conservative Treatment of Endometrial Adenocarcinoma in Young Women: A Case Report and Review of the Literature.年轻女性子宫内膜腺癌长期保守治疗的挑战性方案:一例病例报告及文献综述
Case Rep Oncol. 2010 Oct 25;3(3):380-385. doi: 10.1159/000321731.
2
Controversies in the management of endometrial carcinoma.子宫内膜癌管理中的争议
Obstet Gynecol Int. 2010;2010:862908. doi: 10.1155/2010/862908. Epub 2010 Jun 22.