Uyar Meltem, Eyigör Can
Department of Algology, Medical Faculty of Ege University, Izmir, Turkey.
Agri. 2008 Oct;20(4):6-16.
Treatment of neuropathic pain is difficult despite new treatments and there is no single treatment that Works for all conditions and their underlying mechanisms. Given the increasing evidence for effective treatments of neuropathic pain, it is important for the clinician to know which drugs are most effective neuropathic pain relieving pain and associated with the fewest adverse effects and there is a need for an evidence-based algorithm to treat neuropathic pain conditions. Ideally, the evidence for the non-opioids and opioids choices in such an algorithm would be based on direct comparisons of one drug with another, for both efficacy and side effects. There are very few such direct comparisons available.
尽管有新的治疗方法，但神经性疼痛的治疗仍然困难，没有一种单一的治疗方法适用于所有情况及其潜在机制。鉴于越来越多的证据表明神经性疼痛有有效的治疗方法，临床医生了解哪些药物对缓解神经性疼痛最有效且副作用最少非常重要，并且需要一种基于证据的算法来治疗神经性疼痛病症。理想情况下，这种算法中关于非阿片类药物和阿片类药物选择的证据应基于一种药物与另一种药物在疗效和副作用方面的直接比较。但目前可用的此类直接比较非常少。
