Ersoy Eren, Gündoğdu Haldun, Uğraş Nevzat Serdar, Aktimur Recep
Departments of General Surgery, Atatürk Research and Educational Hospital, Ankara.
Turk J Gastroenterol. 2008 Dec;19(4):268-70.
Diffuse nodular lymphoid hyperplasia represents a rare disease that is grossly characterized by the presence of numerous visible mucosal nodules measuring up to, and rarely exceeding, 0.5 cm in diameter. These may involve the entire small intestine, the large intestine, or both. The etiology is unknown. When diffuse nodular lymphoid hyperplasia is found predominantly in the colon, it can mimic a variety of polyposis syndromes and this may cause difficulties in diagnosis. The disease may be associated with other pathologies, especially gastrointestinal malignancies. This causes controversy when deciding the treatment options. Following patients without any treatment may lead to malignant progression, while surgical treatment may result in unnecessary radical resections because of obscurity in the diagnosis. We report here a diffuse nodular lymphoid hyperplasia case who underwent a radical resection because of obscurity in the diagnosis.
弥漫性结节性淋巴组织增生是一种罕见疾病,其大体特征是存在大量可见的黏膜结节,直径可达0.5厘米,很少超过该尺寸。这些结节可能累及整个小肠、大肠或两者皆有。病因不明。当弥漫性结节性淋巴组织增生主要出现在结肠时,它可能会模仿多种息肉病综合征,这可能导致诊断困难。该疾病可能与其他病理状况相关,尤其是胃肠道恶性肿瘤。这在决定治疗方案时会引发争议。对患者不进行任何治疗可能会导致恶性进展,而手术治疗可能因诊断不明确而导致不必要的根治性切除。我们在此报告一例因诊断不明确而接受根治性切除的弥漫性结节性淋巴组织增生病例。